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Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
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Glycan Biomarker Discovery Solutions

BOC Sciences offers Glycan Biomarker Discovery services for biotech companies, pharmaceutical developers, and research institutions. Our glycomics, glycoproteomics, and bioinformatics expertise support a complete and robust portfolio of analytical and translational services to deliver the highest confidence and clinical relevance for disease-associated glycan signatures. Our Glycan Biomarker Discovery Services support early disease detection, drug development, therapeutic monitoring, and precision medicine applications. From high-resolution LC-MS/MS glycan profiling to artificial intelligence-based data analysis, we work with you to design the right solution for your needs. Our data is biomarker validated and translational ready.

What Problems We Solve?

Traditional biomarker discovery often overlooks the complexity of glycosylation, a critical biological process linked to cancer, autoimmune disorders, infectious diseases, and therapeutic response. Our Glycan Biomarker Discovery services are designed to solve key challenges, including:

Early disease detection: uncovering subtle glycan signatures that appear before conventional biomarkers.

Improved diagnostic accuracy: distinguishing between disease subtypes or stages with higher specificity.

Therapeutic monitoring: tracking glycan changes to evaluate treatment efficacy.

Drug development bottlenecks: providing glyco-profiling insights to enhance biopharmaceutical quality, safety, and regulatory compliance.

Data complexity: simplifying high-dimensional glycomics data with advanced computational pipelines and machine learning.

By addressing these issues, we help healthcare companies, research institutions, and biotech startups accelerate breakthroughs with reliable, glycan-based insights.

Glycan Biomarker Discovery Services

01

Sample Preparation & Enrichment

We ensure high-quality, reproducible sample processing to preserve glycan integrity and maximize discovery potential.

  • Specialized workflows for serum, plasma, tissue, and cell-line samples.
  • Depletion of high-abundance proteins to improve low-level biomarker detection.
  • Lectin-based or affinity-based enrichment for glycoproteins and glycopeptides.
02

Glycan Release, Labeling & Profiling

Our robust methods capture the complexity of glycosylation with high sensitivity and accuracy.

  • Enzymatic and chemical release of N-glycans and O-glycans.
  • Fluorescent or chemical labeling for improved detection sensitivity.
  • Comprehensive glycan profiling for comparative biomarker studies.
03

High-Resolution LC-MS/MS & HPLC Analysis

We provide state-of-the-art analytical platforms for precise glycan identification and quantification.

  • High-resolution LC-MS/MS for site-specific glycopeptide mapping.
  • HPLC and UHPLC workflows for glycan separation and structural elucidation.
  • Quantitative glycomics with advanced fragmentation strategies (HCD, ETD, CID).
04

Lectin & Glycan Microarrays

We offer high-throughput tools to study glycan-protein interactions and biomarker screening.

  • Glycan microarray screening for disease-associated binding patterns.
  • Lectin-based assays to validate glycan biomarker candidates.
  • Multiplex detection to accelerate large-scale studies.
05

Bioinformatics & Data Interpretation

We turn complex glycomics data into actionable insights with AI-driven analytics.

  • Structural assignment using specialized glycan and glycopeptide databases.
  • Differential expression analysis for case-control and longitudinal studies.
  • Machine learning models for biomarker discovery and predictive validation.

Our Competitive Edge

By partnering with us, you gain access to unique strengths that set our Glycan Biomarker Discovery services apart.

Comprehensive End-to-End Solution: From initial consultation to clinical translation, we provide full coverage in a single service pipeline.

Cutting-Edge Technology: High-resolution LC-MS/MS, UHPLC, and AI-powered bioinformatics ensure accuracy, sensitivity, and reproducibility.

Expert Glycoscience Team: Our multidisciplinary experts in glycomics, proteomics, and bioinformatics bring deep domain knowledge to every project.

Customized & Scalable: Flexible service modules adapt to small discovery studies or large validation projects.

Accelerated Timelines: Optimized workflows reduce turnaround time, helping you move faster from discovery to market.

Where Our Services Apply?

Oncology & Cancer Research

  • Early Diagnosis - Detect cancer-associated glycan signatures that appear before traditional protein or genetic markers.
  • Subtype Differentiation - Distinguish between tumor types and stages with higher accuracy.
  • Therapy Monitoring - Track glycosylation changes to evaluate treatment response and recurrence risk.

Autoimmune & Inflammatory Diseases

  • Immune Profiling - Characterize glycan changes in immunoglobulins (IgG, IgA) linked to autoimmune disorders.
  • Biomarker Discovery - Identify glycan biomarkers for diseases such as rheumatoid arthritis, lupus, and IBD.

Infectious Diseases

  • Pathogen Detection - Uncover host-pathogen glycan interactions that signal infection.
  • Disease Progression - Monitor glycosylation patterns as indicators of disease severity.
  • Vaccine Development - Support design of glycan-based vaccines and adjuvant strategies.

Biopharmaceutical Development

  • Quality Control - Ensure therapeutic glycoproteins meet regulatory glycosylation standards.
  • Batch Consistency - Monitor glycan profiles to confirm product stability and reproducibility.

Personalized & Precision Medicine

  • Individualized Risk Assessment - Use glycan biomarkers to evaluate patient-specific disease risk.
  • Companion Diagnostics - Develop assays that link biomarker detection with targeted therapies.
  • Longitudinal Health Tracking - Monitor glycan signatures over time for early intervention.

Project Delivery Process

We follow a streamlined and standardized workflow to ensure every Glycan Biomarker Discovery project is scientifically rigorous and commercially viable.

Requirement Assessment and Project Planning

1Consultation & Project Design

We begin with in-depth discussions to understand your research goals or product development pipeline, and design a customized study plan.

Requirement Assessment and Project Planning

2Sample Preparation & Enrichment

Biological samples are processed using optimized workflows to preserve glycan integrity and reduce background interference.

Requirement Assessment and Project Planning

3Analytical Processing

Advanced technologies such as LC-MS/MS, HPLC, and glycan microarrays are applied to generate high-resolution glycomics data.

Requirement Assessment and Project Planning

4Bioinformatics & Data Interpretation

AI-driven software and specialized glycan databases are used for structural assignment, statistical analysis, and biomarker discovery.

Requirement Assessment and Project Planning

5Validation & Reporting

Candidate biomarkers are validated in extended cohorts, and a comprehensive report with actionable insights is delivered.

Frequently Asked Questions (FAQs)

1. What is Glycan Biomarker Discovery?

It is the process of identifying disease-associated glycan structures or glycoproteins that can be used as diagnostic, prognostic, or therapeutic biomarkers.

We work with serum, plasma, urine, tissue, cell lines, and purified proteins, with optimized workflows tailored to each sample type.

We employ LC-MS/MS, UHPLC, HPLC, glycan microarrays, and AI-powered bioinformatics for comprehensive glycomics profiling.

Our services are designed for pharmaceutical companies, biotech startups and academic researchers seeking to accelerate biomarker discovery.

Partner With Us for Glycan Biomarker Discovery

Ready to transform your research or product pipeline with glycan biomarker discovery? At BOC Sciences, we not only deliver world-class analytical and bioinformatics services, but also provide access to a wide range of specific glycans for research and development. Our portfolio includes N-linked glycans, O-linked glycans, sialylated glycans, fucosylated glycans, mannose-rich glycans, and hybrid/complex glycan structures, available for customized analysis and validation. Whether you are in oncology, immunology, infectious disease, or biopharma development, our team is here to help you accelerate discovery, validate biomarkers, and bring glycan-driven solutions closer to clinical and commercial impact.

Contact us today to discuss your project and explore how our Glycan Biomarker Discovery services can empower your next breakthrough.

* Only for research. Not suitable for any diagnostic or therapeutic use.
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