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Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
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Glycan Capture, Cleanup & Labeling Solutions

We offer specialized capture, cleanup, and labeling services for released glycans, seamlessly integrated into our Glycan Profile platform. By combining optimized sample preparation techniques with advanced analytical workflows, we enable researchers and biopharmaceutical developers to obtain clean, well-characterized glycan samples that are ready for downstream analysis. Our service ensures that released glycans are efficiently isolated, free from interfering contaminants, and enhanced with sensitive labeling strategies, delivering accurate, reproducible, and publication-ready data for glycomics, biomarker discovery, and therapeutic development.

Challenges We Solve

Sample Complexity: Glycan mixtures are often heterogeneous and difficult to purify without losing critical information.

Data Accuracy: Incomplete or poorly labeled glycans can compromise downstream glycan profiling and structural analysis.

Reproducibility: Manual cleanup steps increase variability and reduce consistency across experiments.

Time Efficiency: Inefficient workflows slow down discovery and development pipelines.

Glycan Capture, Cleanup & Labeling Services We Deliver

We provide optimized workflows to ensure efficient and reliable release of glycans from complex biomolecules.

  • Tailored protocols for N-glycan and O-glycan release from glycoproteins and glycolipids.
  • Enzymatic and chemical methods selected based on sample type and research goals.
  • Minimization of sample degradation to preserve glycan integrity.
02

Advanced Cleanup

Our cleanup methods remove unwanted impurities, delivering high-purity glycans for downstream analysis.

  • Effective removal of salts, detergents, and proteins that interfere with detection.
  • Use of solid-phase extraction and other advanced purification techniques.
  • Scalable approaches suitable for both small research samples and large-scale projects.
03

Fluorescent & Isotopic Labeling

We enhance sensitivity and quantification through customized glycan labeling strategies.

  • Wide selection of fluorophores and isotopic tags compatible with LC-MS and HPLC.
  • Improved detection limits for low-abundance glycans.
  • Quantitative labeling to support accurate comparative studies.
04

Method Scalability

Our flexible services adapt to different project sizes and experimental needs.

  • High-throughput solutions for pharmaceutical and biotech pipelines.
  • Customizable protocols for specialized research.
  • Consistent reproducibility across varying sample volumes.
05

Quality Assurance

We ensure every glycan preparation meets the highest standards of accuracy and reliability.

  • Rigorous QC checkpoints throughout capture, cleanup, and labeling.
  • Reproducible results validated with reference standards.
  • Detailed documentation and reporting to support regulatory compliance.

Why Choose Our Services?

By choosing our service, clients gain access to specialized expertise and proven benefits:

High Sensitivity & Accuracy: Optimized labeling and cleanup ensure precise detection, even for low-abundance glycans.

Reproducible Results: Standardized protocols and strict QC guarantee consistency across experiments and projects.

Customizable Solutions: Flexible workflows tailored to academic research and biopharmaceutical pipelines.

Time & Cost Efficiency: Automated and streamlined methods reduce turnaround time and minimize sample loss.

Expert Support: Access to a team of glycan specialists who provide guidance from project planning to data interpretation.

Application Areas

Biopharmaceutical Development

  • Supporting drug design, safety, and efficacy studies.
  • Characterization of glycosylation patterns in therapeutic antibodies and glycoproteins.
  • Ensuring consistency of glycan structures across production batches.
  • Compliance with regulatory requirements for biologics quality control.

Diagnostic Research

  • Enabling biomarker discovery and disease-related glycan profiling.
  • Identification of glycan signatures linked to cancer, autoimmune, and infectious diseases.
  • Improved sensitivity in detecting disease-specific glycan biomarkers.
  • Validation of glycans as diagnostic or prognostic tools in precision medicine.

Academic & Basic Research

  • Advancing fundamental glycoscience studies.
  • Detailed structural analysis of N-glycans and O-glycans in diverse biological systems.
  • Support for glycomics projects in systems biology and cell signaling research.
  • Facilitating publication-ready results with high reproducibility and clarity.

Industrial Biotechnology

  • Enhancing product quality and process optimization.
  • Monitoring glycan profiles in biosimilars and bioprocess development.
  • Improving yield and stability of glycoprotein-based products.
  • Reducing variability in large-scale biomanufacturing workflows.

Our Service Workflow

Our capture, cleanup, and labeling of released glycans service follows a streamlined workflow designed for precision and reproducibility:

Requirement Assessment and Project Planning

1Sample Consultation & Assessment

We evaluate sample type, project goals, and analytical needs to design the optimal workflow.

Requirement Assessment and Project Planning

2Glycan Release

Controlled enzymatic or chemical methods are applied to efficiently release N-glycans or O-glycans from biomolecules.

Requirement Assessment and Project Planning

3Purification & Cleanup

Advanced techniques remove salts, proteins, and contaminants to achieve highly pure glycans.

Requirement Assessment and Project Planning

4Labeling & Enhancement

Glycans are tagged with fluorescent or isotopic labels for sensitive detection and quantification.

Requirement Assessment and Project Planning

5Data-Ready Delivery

Clean, labeled glycans are prepared for downstream analysis such as LC-MS, HPLC, or glycan profiling.

Frequently Asked Questions (FAQs)

1. What types of samples can you process for glycan capture and cleanup?

We can process a wide range of samples, including glycoproteins, glycolipids, therapeutic antibodies, serum, and complex biological mixtures.

We offer both fluorescent tags (e.g., 2-AB, 2-AA) and isotopic labeling strategies, depending on whether your goal is improved detection sensitivity or quantitative analysis.

Yes, our workflow follows strict quality control standards, and we provide detailed reports with documentation suitable for regulatory or publication purposes.

In addition to sample preparation, we can also support glycan profiling and data analysis upon request, ensuring you receive actionable insights.

Take the Next Step

Unlock the full potential of your glycan research with our capture, cleanup, and labeling of released glycans service. Whether you are advancing drug development, validating biomarkers, or conducting fundamental glycoscience studies, our streamlined workflows and expert team will deliver the precision and reliability you need. In addition to our technical services, we also provide access to a wide range of reference glycans and specialized glycan standards to support your experimental design and validation. This means you not only get high-quality service, but also the essential building blocks to accelerate your glycomics research.

Contact us today to discuss your project needs and explore how our Glycan Profile solutions can empower your next breakthrough.

* Only for research. Not suitable for any diagnostic or therapeutic use.
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