webinar
Oct. 27-28, 2025, Boston, MA, USA - Booth 114.
Read More

Specialized Glycan Synthesis Services

We specialize in the custom synthesis of rare, complex, and highly modified glycans, designed to meet the toughest challenges in biopharma, immunology, vaccine research, and diagnostics. From sialic acid derivatives and isotope-labeled glycans to glycolipids, blood group antigens, and branched structures, we provide precisely tailored molecules with verified purity and structure. Each project is supported by our scientific experts, ensuring you get the right glycans, in the right format, ready to accelerate your discovery and development goals.

Problems We Solve

Scarcity of Specialized Glycans - Many critical glycans, such as sialic acid derivatives or glycolipids, are not commercially available in sufficient purity or quantity.

Need for Tailored Molecular Tools - Standard glycan libraries often cannot meet unique project requirements in biopharma, vaccine design, or immunology.

Challenges in Structural Complexity - Branched, isotope-labeled, or chemically modified glycans require expert synthesis and validation beyond routine methods.

Time & Cost Efficiency - Outsourcing glycan synthesis to a specialized team accelerates R&D while reducing the burden of in-house development.

Through our customized solutions, we help researchers and biotech teams overcome these barriers, ensuring access to the exact glycans needed for cutting-edge applications.

Our Services in Specialized Glycan Synthesis

We deliver a full portfolio of specialized glycan synthesis services, each designed to address complex biomedical research and therapeutic development needs.

01

Sialic Acid Monosaccharides

We synthesize Neu5Ac, Neu5Gc, and their derivatives with high precision and purity. These glycans are critical for:

  • Viral Binding Studies - understanding influenza, coronavirus, and other viral recognition mechanisms.
  • Immune Regulation - exploring immune cell signaling, glycan–lectin interactions, and autoimmune pathways.
  • Vaccine Development - providing reliable substrates and antigens for next-generation vaccine design.
02

Rare & Modified Glycans

We create sulfated, phosphorylated, fluorinated, and chemically engineered glycans that are otherwise unavailable or difficult to isolate. These unique molecules are essential for:

  • Biomedical Research - probing signaling pathways and cellular communication.
  • Therapeutics - engineering glycans for increased drug stability or targeted delivery.
  • Diagnostics - developing glycan-based biomarkers for disease detection.
03

Isotope-Labeled Glycans

We offer 13C, 15N, and deuterium-labeled glycans to enable advanced analytical studies, including:

  • Metabolic Flux Analysis - tracing glycan metabolism in cells and tissues.
  • Glycomics Research - enhancing sensitivity and precision in glycan profiling.
  • Biomarker Discovery - supporting studies with accurate isotopic labeling.
04

Glycosaminoglycans (GAGs) & Oligomers

Our services include custom synthesis of heparan sulfate, chondroitin sulfate, and hyaluronic acid fragments. These play vital roles in:

  • Tissue Engineering - scaffolds and biomaterials for regenerative medicine.
  • Signaling Pathway Studies - investigating cell growth, adhesion, and migration.
  • Therapeutic Applications - modulating angiogenesis, inflammation, and wound healing.
05

Glycolipids & Glycosphingolipids

We produce GM1, GM3, Globo H, Lewis antigens, and more, with applications in:

  • Cancer Immunotherapy - as tumor-associated carbohydrate antigens for vaccine design.
  • Neurological Research - studying neurodegenerative diseases and synaptic processes.
  • Cell–Cell Interaction Studies - understanding membrane biology and recognition events.
06

Blood Group Antigen Glycans

We supply ABO, H, and Lewis antigen glycans for:

  • Transfusion Medicine - developing safer blood-matching and compatibility assays.
  • Diagnostic Assays - creating reagents for precise immunohematology testing.
  • Immune System Research - studying natural antibody responses and immune tolerance.
07

Pathogen-Associated Glycans

We synthesize bacterial capsular polysaccharides and viral glycan epitopes, which are essential for:

  • Vaccine Design - building carbohydrate-based immunogens against infectious diseases.
  • Host–Pathogen Studies - analyzing how microbes exploit glycans for invasion.
  • Therapeutic Research - designing inhibitors to block pathogen–glycan binding.
08

Branched & Complex Glycans

We provide multi-antennary, bisected, and highly modified glycan structures to support:

  • Therapeutic Antibody Development - improving Fc glycosylation for enhanced efficacy.
  • Protein Folding & Stability Studies - ensuring correct glycoprotein conformation.
  • Advanced Biopharma Applications - enabling the design of next-generation biologics.

Why Choose Us for Specialized Glycan Synthesis?

Choosing us means gaining more than just a synthesis service - you get a reliable partner for innovation in glycobiology and biopharma.

Unmatched Customization: From sialic acids to branched glycan structures, we deliver fully tailored molecules that standard catalogs cannot provide.

Broad Portfolio Coverage: Our expertise spans rare glycans, isotope-labeled glycans, GAGs, glycolipids, blood group antigens, and pathogen-associated glycans, ensuring a one-stop solution.

Cutting-Edge Technology: We integrate both chemical and enzymatic synthesis platforms, backed by state-of-the-art analytical tools, to guarantee structural precision.

Scalability from Research to Preclinical Needs: We support projects from milligram-level synthesis for discovery research up to gram-scale production for therapeutic development.

Expert Scientific Team: Our chemists and glycobiologists bring deep experience in glycomics, immunology, oncology, and diagnostics, ensuring your project benefits from domain expertise.

Accelerated Timelines & Cost Efficiency: By outsourcing specialized glycan synthesis, you save valuable time, resources, and infrastructure costs, while receiving reliable results faster.

Applications of Specialized Glycan Synthesis

Our Specialized Glycan Synthesis services support a wide range of scientific and biomedical fields. By providing custom-designed glycans, we enable breakthroughs in both fundamental research and translational medicine.

Drug Discovery & Development

  • Target Identification - Custom glycans help map glycan–protein interactions critical for drug target validation.
  • Lead Optimization - Modified glycans improve drug stability, solubility, and delivery efficiency.
  • Therapeutic Antibody Engineering - Branched or bisected glycans support Fc glycoengineering for enhanced efficacy.

Vaccine Research

  • Carbohydrate-Based Antigens - Pathogen-associated glycans serve as building blocks for next-generation vaccines.
  • Sialic Acid Studies - Neu5Ac and Neu5Gc derivatives enable the design of viral binding inhibitors.
  • Conjugate Vaccines - Ready-to-conjugate glycans simplify the development of glycoconjugate vaccines.

Immunology & Infectious Diseases

  • Host–Pathogen Interactions - Bacterial and viral glycans help study mechanisms of infection.
  • Immune Recognition - Blood group antigens and glycolipids reveal how the immune system differentiates self from non-self.
  • Autoimmunity Models - Modified glycans provide insights into abnormal glycan–antibody responses.

Oncology & Cancer Immunotherapy

  • Tumor Biomarker Discovery - Tumor-associated glycans like Globo H or GM3 identify cancer-specific targets.
  • Vaccine Development - Carbohydrate antigens are applied in therapeutic cancer vaccine pipelines.
  • Glycan–Immune Modulation - Engineered glycans help study immune evasion in the tumor microenvironment.

Neurological Research

  • Neurodegenerative Disease Models - Glycosphingolipids such as GM1 and GM3 are critical in Parkinson's and Alzheimer's research.
  • Synapse Function Studies - Specialized glycans regulate synaptic plasticity and neurotransmission.
  • Membrane Biology - Glycolipids support research into neuron–glia interactions and signaling.

Diagnostics & Biomarker Development

  • Isotope-Labeled Glycans - 13C and 15N glycans enhance biomarker discovery in glycomics workflows.
  • High-Sensitivity Assays - Custom glycans provide reference standards for diagnostic assay validation.
  • Disease Profiling - Rare glycans enable differential analysis of healthy vs. disease states.

Regenerative Medicine & Tissue Engineering

  • Biomaterial Design – GAG fragments such as hyaluronic acid support scaffold development.
  • Cell Signaling Studies – Tailored glycans regulate pathways essential for wound healing and regeneration.
  • Therapeutic Delivery – Modified glycans enhance drug or growth factor incorporation into biomaterials.

Service Workflow - How We Deliver Specialized Glycan Synthesis?

We follow a streamlined yet rigorous process to ensure every glycan we deliver meets the highest standards of precision, reproducibility, and scientific value.

Requirement Assessment and Project Planning

1Consultation & Project Design

We start with an in-depth discussion of your research or therapeutic goals.

Our experts help define structural requirements, scale, modifications, and analytical needs.

Requirement Assessment and Project Planning

2Custom Strategy Development

Requirement Assessment and Project Planning

3Synthesis & Optimization

Requirement Assessment and Project Planning

4Analytical Validation

Requirement Assessment and Project Planning

5Delivery & Ongoing Support

Frequently Asked Questions (FAQs)

1. What types of glycans can you synthesize?

We offer a broad portfolio, including sialic acids, rare/modified glycans, isotope-labeled glycans, glycosaminoglycans, glycolipids, blood group antigens, pathogen-associated glycans, and branched/complex glycans.

We provide milligram-level quantities for research and can scale up to gram-level production for preclinical or industrial applications.

All glycans undergo comprehensive structural validation using MS, NMR, and HPLC. We also provide a detailed data package for each project to confirm purity and identity.

Yes. We specialize in chemical modifications and isotopic labeling, as well as adding linkers or tags for conjugation and assay development.

Absolutely. Our team provides scientific consultation to refine requirements, assess feasibility, and recommend the best synthesis strategy for your goals.

Ready to Accelerate Your Research with Specialized Glycan Synthesis?

Partner with us to access rare, customized, and high-purity glycans that drive innovation in drug discovery, vaccine development, diagnostics, immunology, and regenerative medicine. Our team not only delivers glycans with verified structural integrity but also provides ready-to-use glycans that can be directly conjugated for your downstream applications.

We can supply:

Whether you need sialic acid derivatives, glycolipids, blood group antigens, or branched glycan structures, we can deliver them ready for conjugation, saving you time and ensuring seamless integration into your experiments.

Contact us today to discuss your project requirements and discover how our Specialized Glycan Synthesis services can accelerate your next breakthrough.

* Only for research. Not suitable for any diagnostic or therapeutic use.
Send Inquiry
Verification code