We provide comprehensive Glycan Profile services to support biopharmaceutical companies, research institutions, and laboratories in understanding the complexity of glycosylation. Our platform combines advanced enzymatic digestion, glycan labeling, and state-of-the-art LC-MS/UPLC/CE technologies to deliver accurate, reproducible, and regulatory-ready results. Whether you need to ensure batch-to-batch consistency, explore disease biomarkers, or validate therapeutic protein quality, our glycan profiling solutions are designed to accelerate your projects with precision and confidence.
Biopharmaceutical Quality Control: Glycosylation directly impacts drug safety, stability, and efficacy. We help detect and quantify glycan structures.
Batch Consistency & Comparability: Ensure your monoclonal antibodies and recombinant proteins show consistent glycosylation patterns across production runs.
Regulatory Submissions: Generate reliable data packages for IND, BLA, or biosimilar applications.
Disease Biomarker Discovery: Identify glycan alterations linked to cancer, inflammation, or metabolic disorders.
Research Acceleration: Save time and resources with expert glycan analysis that translates complex data into actionable insights.
We provide precise enzymatic and chemical release of glycans to ensure maximum recovery and structural integrity:
Our glycan purification and labeling workflow maximizes sensitivity and accuracy:
We apply multiple orthogonal analytical platforms to build a comprehensive glycan profile:
We offer a full suite of structural characterization techniques to analyze and confirm the molecular features of glycans, proteins, and related biomolecules with precision.
We deliver actionable glycan data in publication- and regulatory-ready formats:
Our Release of Glycans service is compatible with a wide range of biological and biopharmaceutical samples, ensuring flexibility and reliability for different research and industrial applications.
Partnering with us gives you access to cutting-edge glycan analysis and dedicated expert support:
Comprehensive Coverage: Full workflow from glycan release to regulatory-ready reporting.
High Sensitivity & Accuracy: State-of-the-art LC-MS/UPLC/CE platforms detect even low-abundance glycans.
Customizable Solutions: Tailored profiling strategies for therapeutic proteins, biosimilars, vaccines research.
Expertise & Experience: A team of glycoanalysis specialists with years of experience in biopharmaceutical quality control and biomarker discovery.
Fast Turnaround: Optimized workflow ensures timely results without compromising quality.
Value-Added Insights: Beyond raw data, we provide actionable interpretations that accelerate drug development and research.
Our Glycan Profile Service has broad applications across the biopharmaceutical and research landscape. Below are the key areas with detailed focus points:
Our Glycan Profile Service follows a streamlined, step-by-step workflow to ensure accuracy, reproducibility, and regulatory compliance:
Clients provide protein, antibody, vaccine, or biological samples.
Our experts discuss project goals, target glycans, and regulatory requirements.
Enzymatic or chemical release of N- and O-linked glycans with optimized protocols for maximum yield.
Removal of impurities, followed by fluorescent or MS-friendly glycan labeling to enhance detection sensitivity.
Advanced platforms (HILIC-UPLC, CE, LC-MS, MALDI-TOF MS) deliver a complete glycan fingerprint.
Quantitative reports including fucosylation, galactosylation, sialylation, high-mannose, and branching ratios.
One-on-one expert discussion to interpret findings, answer questions, and suggest next steps.
A glycan profile is the detailed map of N- and O-linked glycans present on proteins, antibodies, or biological samples. It shows the types, structures, and relative abundance of glycans, providing critical insights into protein function, stability, and therapeutic quality.
Glycosylation impacts drug safety, stability, efficacy, and immunogenicity. Regulatory agencies (FDA, EMA, ICH) require glycan profiling as a critical quality attribute (CQA) in biopharmaceutical submissions.
We accept monoclonal antibodies, recombinant proteins, vaccines, serum/plasma, and other biological materials. Our methods are adaptable to a wide range of sample sources.
We combine HILIC-UPLC, Capillary Electrophoresis (CE), LC-MS, and MALDI-TOF MS to provide comprehensive, high-resolution glycan profiling.
Absolutely. We provide tailor-made workflows, from method development and validation to biomarker discovery and advanced glycomics research.
Ready to unlock the power of glycan profiling for your biologics or research project? Our team of experts is here to deliver accurate, regulatory-compliant results that accelerate your development pipeline and strengthen your scientific discoveries. Beyond profiling services, we can also provide access to well-characterized glycans, including:
Contact us today to discuss your project, request a customized quotation, or schedule a free consultation with our glycan specialists. Together, we'll bring clarity and confidence to your glycosylation analysis.
