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  6. Interleukin Related
  7. Pentagalloylglucose
Pentagalloylglucose
Pentagalloylglucose Chemical Structure

Pentagalloylglucose

Catalog NO.: B2703-000055 CAS NO.: 14937-32-7 Brand: BOC Sciences

Category
Inhibitor
Tag/Targets
Interleukin Related
Molecular Formula
C41H32O26
Molecular Weight
940.68
Size Price Stock Quantity
100 mg $439 In stock
1 g $999 In stock

Request another packsize? Click Bulk Order.

WARNING: Please kindly note that our products are not to be used for therapeutic purposes and cannot be sold to patients.

cGMP Capacity

  • kg to MT scale
  • GMP batches production
  • Over 20 years of experience
  • HPAPI production with OEL < 1 μg/m³
  • Cleanroom Class 100 to Class 100,000
  • Special type of reactions in cGMP workshop
  • Cleaning level: Class A B C
  • cGMP synthesis workshop
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Product Description

Pentagalloylglucose, a polyphenol isolated from the fruits of Pistacia lentiscus, increases a population of Treg cells in conjunction with Treg-inducing factors so that it inhibits IgE production partially. Besides, it suppresses interleukin (IL)-4 induced signal pathway in B cell.

Quantity
Grams-Kilos
Boiling Point
1365.7±65.0 °C | Condition: Press: 760 Torr
Melting Point
143 °C
Density
2.05±0.1 g/cm3
InChI Key
QJYNZEYHSMRWBK-NIKIMHBISA-N
InChI
InChI=1S/C41H32O26/c42-17-1-12(2-18(43)28(17)52)36(57)62-11-27-33(64-37(58)13-3-19(44)29(53)20(45)4-13)34(65-38(59)14-5-21(46)30(54)22(47)6-14)35(66-39(60)15-7-23(48)31(55)24(49)8-15)41(63-27)67-40(61)16-9-25(50)32(56)26(51)10-16/h1-10,27,33-35,41-56H,11H2/t27-,33-,34+,35-,41+/m1/s1
SMILES
C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C(C(C(C(O2)OC(=O)C3=CC(=C(C(=C3)O)O)O)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C(=C5)O)O)O)OC(=O)C6=CC(=C(C(=C6)O)O)O
HPLC
MS
Write a review Ask a question

Excuse me, What is the biological effect of Pentagalloylglucose?

Pentagalloylglucose (Penta-O-galloyl-β-D-glucose) is a gallotannin isolated from various plants and possesses significant anti-rabies virus (RABV) activity.

12/3/2019

Dear team, What is the hypoglycemic mechanism of Pentagalloylglucose?

Pentagalloylglucose can reduce blood sugar levels by promoting insulin secretion and tissue utilization.

2/6/2021

Could you arrange any information about the antitumor effect of Pentagalloylglucose?

Pentagalloylglucose has a significant inhibitory effect on various tumor cells, promoting tumor cell apoptosis, inhibiting its proliferation, and reducing the risk of tumor blood supply and metastasis.

21/2/2022

inhibit IgE production

Satisfied with the product. In my survey, Pentagalloylglucose inhibited IgE production partially caused by increasing a population of Treg cells in conjunction with Treg-inducing factors.

24/5/2016

reduce blood lipid levels

Under our in-depth research, we found out that Pentagalloylglucose could reduce blood lipid levels, inhibit platelet aggregation and vascular inflammatory reactions, thus having a certain protective effect on cardiovascular system. I was content with the material.

3/5/2017

suppress interleukin (IL)-4 induced signal pathway

As expected, in my cell experiment, I found out that Pentagalloylglucose could suppress interleukin (IL)-4 induced signal pathway in B cell.

15/10/2018

1.Efficacy of the MAGE-A3 cancer immunotherapeutic as adjuvant therapy in patients with resected MAGE-A3-positive non-small-cell lung cancer (MAGRIT): a randomised, double-blind, placebo-controlled, phase 3 trial.
Vansteenkiste JF1, Cho BC2, Vanakesa T3, De Pas T4, Zielinski M5, Kim MS6, Jassem J7, Yoshimura M8, Dahabreh J9, Nakayama H10, Havel L11, Kondo H12, Mitsudomi T13, Zarogoulidis K14, Gladkov OA15, Udud K16, Tada H17, Hoffman H18, Bugge A19, Taylor P20, Gon Lancet Oncol. 2016 Apr 27. pii: S1470-2045(16)00099-1. doi: 10.1016/S1470-2045(16)00099-1. [Epub ahead of print]
BACKGROUND: Fewer than half of the patients with completely resected non-small-cell lung cancer (NSCLC) are cured. Since the introduction of adjuvant chemotherapy in 2004, no substantial progress has been made in adjuvant treatment. We aimed to assess the efficacy of the MAGE-A3 cancer immunotherapeutic in surgically resected NSCLC.
About Us

BOC Sciences is a trusted global supplier of research chemicals, biochemicals, and pharmaceutical ingredients, serving the life sciences, biotech, and pharmaceutical industries. Headquartered in New York, we offer a comprehensive product portfolio that includes inhibitors, building blocks, carbohydrates, nucleosides, nucleotides, GMP products, impurities and metabolites, APIs, natural compounds, ADC-related chemicals, and stem cell molecules.

We specialize in the synthesis, biosynthesis, purification, and characterization of small molecules. With years of industry experience, our scientific and technical teams support projects ranging from early discovery to process development and regulatory submission.

BOC Sciences operates GMP-compliant and ISO-certified production facilities, ensuring consistent quality and regulatory alignment. Our products and services are trusted by clients in over 60+ countries, including top pharmaceutical companies, academic institutions, and research organizations.

We are committed to providing high-quality chemicals, responsive technical support, and flexible custom solutions to accelerate innovation in drug discovery and development.

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