Nucleotides Services

Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers deoxyribonucleic acid (DNA) and ribonucleic acid (RNA), both of which are essential biomolecules within all life-forms on Earth. Nucleotides are the building blocks of nucleic acids; they are composed of three subunit molecules: a nitrogenous base, a five-carbon sugar (ribose or deoxyribose), and at least one phosphate group. Some nucleotides are linked up one another by phosphodiester bond to form a strand, the backbone of DNA or RNA. RNA merely consists of one strand; however, DNA consists of two strands. Hydrogen bonds between the nitrogenous bases hold the two strands together of the double helix structure.

Application

Our Services

BOC Sciences can provide a number of nucleotide related services including but not limited to:

  • Gene Synthesis and Cloning Service
  • Gene Mutagenesis Service
  • Oligonucleotide Synthesis Service
  • DNA Methylation Analysis Services
  • Plasmid DNA Production Service
  • Gene Expression Service

Why Choose BOC Sciences?

  • BOC Sciences synthesizes nucleotides by automated solid-phase methods.
  • Rich experience in research and manufacture of nucleotides and their analogue, including customized nucleotides synthesis and nucleotides analog synthesis and analysis service.
  • More than a decade of nucleotides service experience allows us to offer the highest level of quality control over the synthesis of every custom ordered product.
  • Rich expertise of our scientists also makes fast turn around and the best customer support available.

We have lots of compounds in stock, and our existing libraries of building blocks alongside with our specialized expertise allow short cut access to any desired novel nucleotide structure. In short, we are convinced that our custom nucleotides synthesis service will meet or exceed your expectations. For additional information and for peptide synthesis pricing, please contact us!

References

  1. Schrum, J. P., Siddiqi, S., & Ejebe, K. (2016). U.S. Patent No. 9,334,328. Washington, DC: U.S. Patent and Trademark Office.
  2. Feng, P., Ding, H., Yang, H., Chen, W., Lin, H., & Chou, K. C. (2017). iRNA-PseColl: identifying the occurrence sites of different RNA modifications by incorporating collective effects of nucleotides into PseKNC. Molecular Therapy-Nucleic Acids7, 155-163.
  3. Peng, C. K., Buldyrev, S. V., Havlin, S., Simons, M., Stanley, H. E., & Goldberger, A. L. (1994). Mosaic organization of DNA nucleotides. Physical review e49(2), 1685.