The objective of this study was to evaluate the nutrient uptake, biomass production and yield of the major compounds in the essential oil of five genotypes of Coriandrum sativum L. The treatments were composed for four accessions provided by the National Genetic Resources Advisory Council (NGRAC), U.S. Department of Agriculture's Agricultural Research Service (USDA/ARS) germplasm: ("AMES 18596"; "PI 171592"; "AMES 4998" and "PI 193770") and one commercially available cultivar, (Santo). Plants were harvested 50 days after sowing and evaluated for nutrient uptake, the number of leaves, fresh and dry weight of shoot per plant and yield of major compounds in the essential oil. Accessions AMES 18596 and PI 171592 presented the following order of accumulation of macronutrients: K > N > Ca > Mg > P > S. For the accessions AMES 4998, PI 193770 and the cultivar Santo, the order K > N > Ca > P > Mg > S was observed. Micronutrients accumulation in cilantro shoot in descending order for all genotypes was: Fe > Zn > B > Mn > Cu. The highest number of leaves per plant was found in the accession AMES 18596 (9.94), while the others produced on average 7.24. Accessions AMES 18596 and PI 193770 produced 7.34 g plant−1 of fresh weight of shoots. Accession PI 171592 produced slightly higher yields (6.23 g plant−1) than the cultivar Santo and AMES 4998 (4.75 g plant−1). For dry weight of shoots, accessions AMES 18596 and PI 193770 produced the highest yields (0.58 g plant−1), followed by PI 171592 (0.47 g plant−1) and the accession AMES 4998 and the cultivar Santo that had on average 0.35 g plant−1. The yield of the major compounds in the essential oil was higher for accessions AMES 18596 and PI 193770 (88.84 μg plant−1) following by AMES 4998 and Santo (38.95 μg plant−1) and PI 171592 (23.31 μg plant−1). On average the yield of aliphatic aldehydes in fresh weight followed the order: trans-2-dodecenal > decanal > trans-2-decenal > tetradecenal > dodecanal > tetradecanal.