BOC Sciences Blog

What is Peptide Nucleic Acid (PNA)

What is Peptide Nucleic Acid (PNA)?

Peptide Nucleic Acid (PNA) is a synthetic polymer similar to DNA or RNA. PNA can be said to have been born in Denmark, where it was originally developed by Peter E. […]

General Design Methods for mRNA Drugs

General Design Methods for mRNA Drugs

With the rapid development of biotechnology and molecular medicine, the introduction of mRNA as a vaccine or therapeutic agent enables the production of almost any desired functional protein/peptide within the […]

Clinical Prospects of Aptamer Applications

Clinical Prospects of Aptamer Applications

Aptamers are short RNA/DNA oligonucleotide molecules that bind specifically to complementary target molecules. As potential recognition elements, aptamers show promising applications in both diagnosis and treatment. They offer diverse therapeutic and diagnostic […]

CD137/4-1BB combination therapy

Two Paths of Second-Generation 4-1BB Agonists

CD137/4-1BB combination therapy

Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action

Hypoglycemic Functional Factors in Natural Products and Their Mechanisms of Action

Diabetes is a common clinical disease, and with the improvement of living standards, an increase in the number of obese people, and the intensification of aging populations, the incidence of […]

Mechanism of Action of Paclitaxel

Mechanism of Action of Paclitaxel

Paclitaxel is a natural anticancer drug with the molecular formula C47H51NO14. It has been widely used in the clinical treatment of breast cancer, ovarian cancer, and certain head and neck cancers, […]

Covalent, Non-covalent, and Covalent Reversible Drug Design in Medicinal Chemistry

Covalent, Non-covalent, and Covalent Reversible Drug Design in Medicinal Chemistry

Chemical drugs can be classified into three categories based on their binding modes: covalent drugs, non-covalent drugs, and covalent reversible drugs. Covalent drugs have strong binding ability and high efficacy, […]

Research progress on adjuvants for influenza vaccines

Research Progress on Adjuvants for Influenza Vaccines

Influenza is an acute and highly contagious respiratory disease caused by influenza A and B viruses. Annual influenza epidemics are caused by several different seasonal influenza viruses (i.e., A/H1N1, A/H3N2, B/Yamagata, […]

Types of Delivery Systems of mRNA Cancer Vaccines

Types of Delivery Systems of mRNA Cancer Vaccines

Brief Description of mRNA Delivery Systems As a therapeutic use, mRNA cancer vaccines have the advantages of high safety, strong immune activation ability, and short production cycle. Moreover, mRNA cancer […]

Review of Popular Targets

Review of Popular Targets

In recent years, antibody therapies (including traditional antibodies and nano-antibodies) have become an important means of treating a wide range of human malignant diseases, and more than 100 antibody therapies […]