A mass of studies have revealed that mTOR is a serine/threonine protein kinase closely related to the occurrence of A mass of studies have revealed that mTOR is a serine/threonine […]
As the basic substance of life, carbohydrate molecules participate in almost all aspects of life activities and play various important biological functions. Based on the extensive biological functions of carbohydrate, […]
The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role […]
What are lipid nanoparticles? Lipid nanoparticles (LNPs) are nanoparticles composed of lipids. They have been developed as vehicles for small molecule delivery by the nanomedicine and materials communities and are […]
Compared with conventional drugs, nucleic acids have great advantages. The mechanism of action and high specificity of nucleic acids provide possible therapeutic approaches for viral infections, various cancers and inoperable […]
Oligonucleotides are short synthetic DNA or RNA polymers, which modulate gene expression through Watson-Crick base pairing with targeted nucleic acids. Oligonucleotides regulate gene expression through a series of processes, including […]
Abstract Immunotherapy has become an indispensable part of cancer treatment. A pivotal phagocytosis checkpoint, named cluster of differentiation 47 (CD47), which functions as a ‘don’t eat me’ signal to protect […]
The development of antibody-drug conjugates (ADCs) has progressed significantly over the past decade due to improvements in payloads, linkers, and conjugation methods. In particular, linker design plays a key role […]
Introduction of Vaccine Adjuvant Adjuvant, also known as immune modulator or Immunepotentiator, is an additive of vaccine. When injected into the body before or mixed with antigen, it can enhance […]
The parent skeleton of Dipyrromethene Boron Difluoride (BODIPY) is a large rigid planar structure, which is composed of two pyrrole rings and a six membered boron nitrogen heterocycle. Because of […]