As of now, a total of 17 ADC drugs have been approved and marketed globally, among which 5 are conjugated via lysine residues. Product Name Company Target DAR Toxin Linker […]
Click chemistry has developed organic reaction methodologies that are rapid, effective, and specifically selective, and its reaction system is not sensitive to oxygen or water. This article first reviews the […]
Flavors and fragrances are pivotal in the food industry, enhancing the sensory attributes of food products and significantly influencing consumer preferences. Fragrances are added in small amounts in the food […]
The parent skeleton of Dipyrromethene Boron Difluoride (BODIPY) is a large rigid planar structure, which is composed of two pyrrole rings and a six membered boron nitrogen heterocycle. Because of […]
Drug Modification Drug modification involves altering the chemical structure of the drug itself (such as functional groups, amino acids or nucleic acid skeletons) and coupling the drug with known partial […]
Earlier we talked about the structure of biotin, which is composed of lipophilic heterocycles and hydrophilic carboxylic acid chains. Therefore, the carboxyl group on the hydrophilic carboxylic acid chain of […]
Biotin, also known as vitamin H and coenzyme R, belongs to the vitamin B family (B7) and is a water-soluble vitamin. As a coenzyme of carboxylase, biotin participates in the […]
Magnetic Beads (MBs) cell sorting is a highly specific cell sorting technology that integrates fields of immunology, cell biology, and magnetism. Its high specificity comes from the specific recognition between antigens […]
This article takes stock of the latest clinical development pipelines for cervical cancer, pancreatic cancer, and leukemia. We calculated clinical trial data for clinical phase Ⅰ, phase Ⅱ, and phase Ⅲ of […]
Although the role of autophagy in cancer is very complex, various pharmacological agents with different antineoplastic properties have been shown to induce autophagic activity resulting in massive death of cells […]