Our dedicated service platform provides comprehensive lipid nanoparticle formulation expertise to deliver exceptional performance. Our team of experts combined with modern equipment enables us to develop optimized LNP formulations which meet your specific needs while providing stable and efficient solutions for drug delivery applications. Our commitment extends to full project support starting from laboratory research through to commercialization by providing complete solutions for lipid nanoparticle technology research and application.
Customized Formulation Development: We design exclusive lipid nanoparticle formulations tailored to clients’ specific needs, such as drug types, therapeutic targets, and application scenarios. Whether for hydrophobic drugs, hydrophilic drugs, or gene therapy agents (such as siRNA, mRNA, etc.), we offer precise customized formulation solutions to achieve optimal drug delivery performance and therapeutic outcomes.
Formulation Optimization Services: For existing LNP formulations, we apply advanced analytical technologies and professional R&D expertise to carry out further optimization. This includes adjusting lipid component ratios, particle size, surface charge, and other parameters to enhance drug encapsulation efficiency, stability, bioavailability, and targeting ability-ultimately improving therapeutic efficacy and reducing potential side effects.
Drug Release Profile Design: Based on therapeutic needs and drug mechanisms of action, we design drug release characteristics for lipid nanoparticles. We offer solutions for sustained release, rapid release, or smart release systems that respond to specific physiological environments (such as pH, temperature, enzymes, etc.), achieving precise drug release within the body, prolonging drug action duration, and enhancing therapeutic effects.
Small-Scale Preparation: Using high-precision laboratory equipment and advanced preparation techniques, we conduct small-scale lipid nanoparticle (LNP) production. This service is ideal for early-stage research and development, formulation screening, and optimization processes. We can rapidly provide small batches of samples to support clients' in vitro studies, cell experiments, and preliminary in vivo efficacy evaluations, effectively shortening the R&D cycle and reducing development costs.
Pilot-Scale Production: Building on successful small-scale preparation, we offer medium-scale pilot production. By optimizing production processes and controlling critical parameters, we ensure consistent quality and performance of lipid nanoparticles as production scales up. Pilot production provides sufficient samples for subsequent preclinical research and commercialization preparation, helping clients advance their projects efficiently and accelerate product launches.
Large-Scale Commercial Production: Equipped with mature industrial production facilities and a rigorous quality management system, we offer large-scale commercial manufacturing services for lipid nanoparticles. We strictly adhere to Good Manufacturing Practices (GMP) and other relevant standards to ensure stable, reliable product quality that meets market demands, empowering clients to achieve commercial success with their products.
Comprehensive Quality Testing: We utilize advanced analytical instruments and techniques to perform comprehensive quality testing of lipid nanoparticles. This includes particle size and distribution measurement, zeta potential analysis, morphological observation, drug encapsulation efficiency and loading capacity assessment, and lipid composition analysis. Our testing ensures that product quality meets predefined standards and client requirements, providing strong support for product safety and efficacy.
Stability Evaluation: We systematically assess the stability of lipid nanoparticles under various storage conditions, such as temperature, humidity, and light exposure. Through long-term stability studies and accelerated stability testing, we predict quality changes during the product’s shelf life. This provides clients with scientific data to determine the product’s expiration date and storage conditions, helping them develop reasonable production and marketing plans.
Biocompatibility Evaluation: We conduct biocompatibility studies of lipid nanoparticles to assess their safety in vivo. This includes cytotoxicity assays, hemocompatibility tests, and immunogenicity studies, ensuring that the product demonstrates excellent biocompatibility during application. Our evaluations help minimize potential adverse reactions and safeguard patient safety during medication use.
We discuss client needs in detail, assess project feasibility and cost, and offer professional recommendations.
We create a detailed development plan and quotation based on requirements, and confirm collaboration after client approval.
We develop and optimize lipid nanoparticle formulations, fine-tuning materials and processes to achieve the best performance.
We perform pilot production to verify process stability and prepare for larger-scale manufacturing.
We conduct full quality testing, including particle size, encapsulation efficiency, stability, and safety evaluations.
We deliver products with full technical documentation and provide ongoing technical support and optimization services.
Professional R&D TeamOur experienced nanotechnology and pharmaceutical experts design precise lipid nanoparticle formulations tailored to client needs.
Advanced Technology PlatformUsing world-class equipment and microfluidic technology, we ensure uniform particle size, high encapsulation efficiency, and excellent nanoparticle stability.
Customized ServicesWe deliver personalized lipid nanoparticle solutions for drug delivery, gene therapy, cosmetics, and more.
Strict Quality ControlOur comprehensive quality system monitors every step, ensuring products meet international standards with high biocompatibility and low toxicity.
Comprehensive After-Sales SupportWe offer technical consulting, product support, and quick problem-solving to help clients successfully advance their projects.
Fast R&D CycleThrough efficient teamwork and advanced methods, we accelerate formulation development, helping clients shorten time-to-market and boost competitiveness.
Enhancing Drug Solubility and Bioavailability: Lipid nanoparticles improve the solubility and absorption of poorly water-soluble drugs, boosting their bioavailability. For example, they enhance the effectiveness of anticancer drugs.
Targeted Drug Delivery: Lipid nanoparticles can be modified to target specific disease sites, improving drug delivery to tumors while minimizing harm to healthy tissues, enhancing safety and efficacy.
Controlled and Sustained Release Formulations: Lipid nanoparticles offer controlled release, ensuring slow and sustained drug delivery. This reduces administration frequency, benefiting chronic disease treatments.
mRNA Delivery: Lipid nanoparticles are used to deliver mRNA into cells, enabling protein expression for gene therapy, as seen in COVID-19 vaccines.
siRNA Delivery: Lipid nanoparticles efficiently deliver siRNA to silence specific genes, providing a therapeutic approach for diseases like cancer.
Enhancing Immunogenicity: Lipid nanoparticles boost immune responses by delivering antigens to immune cells, improving vaccine effectiveness and antibody production.
Improving Vaccine Stability: Lipid nanoparticles protect vaccine antigens from degradation, enhancing stability and shelf life.
Applications in Medical Imaging: Lipid nanoparticles can carry contrast agents for MRI and CT scans, targeting diseased tissues for better imaging accuracy and early disease detection.
Disease Monitoring and Treatment Evaluation: Lipid nanoparticles enable real-time monitoring of disease progression and therapy response, like visualizing tumors during cancer treatment.
Cosmetics: Lipid nanoparticles improve the delivery of active ingredients in cosmetics, enhancing their effects on skin moisture, antioxidants, and whitening.
Food Industry: Lipid nanoparticles improve the stability and bioavailability of bioactive components in food products, such as vitamins and flavors.
We offer a wide range of lipid nanoparticle formulation services, including Solid Lipid Nanoparticles (SLNs), Nanostructured Lipid Carriers (NLCs), and Lipid Nanoparticles (LNPs). Our services are tailored to meet the application needs across various fields such as drug delivery, healthcare products, and cosmetics.
Yes, we offer fully customized services. You can submit your specific requests based on your target compound, intended application, and special requirements. Our professional team will design the most suitable formulation plan for you, including the selection of appropriate lipid materials, emulsifiers, and the optimization of preparation processes.
We have a strict quality control system in place. Starting from raw material procurement, we rigorously screen and evaluate our suppliers to ensure the quality and purity of materials. Throughout the preparation process, every step is closely monitored for quality, including particle size analysis, zeta potential measurement, drug loading, and encapsulation efficiency determination. Once the product is completed, it undergoes comprehensive quality testing and evaluation. Only products that meet our quality standards will be delivered to our customers.
