Oligonucleotides are short synthetic DNA or RNA polymers, which modulate gene expression through Watson-Crick base pairing with targeted nucleic acids. Oligonucleotides regulate gene expression through a series of processes, including […]
In the latest issue of the JMC journal, a review article, entitled “A Decade of FDA-Approved Drugs (2010-2019): Trends and Future Directions”, was published, which analyzed and summarized the FDA-approved […]
16 Metabolic Disease Drugs In February, the FDA approved Esperion Therapeutics’ Nexletol and Nexlizet respectively. On the basis of controlling diet and taking the maximum tolerated dose of statins, both […]
The Janus kinase (JAK1) inhibitor Figotinib (Jyseleca; Gilead) was approved in Japan and the European Union in September 2020. The approved indication in Japan is the treatment of patients with […]
13 Anti-tumor drugs Trastuzumab deruxtecan (Enhertu), an antibody drug conjugate (ADC) developed by Japan’s Daiichi Sankyo and authorized by AstraZeneca for co-development and commercialization, was approved by the FDA at […]
12 Immunomodulators and immunotherapy drugs AimmuneTherapeutautics has achieved an important goal this year: Palforzia (Arachishypogaea allergen powder-dnfp) was approved by the FDA and listed for the first time. Palforzia is […]
11 Anti-infective drugs The 2020 COVID-19 pandemic will linger in everyone’s memory forever. In this year, Remdesivir (Veklury; Gilead), as the first anti-viral treatment of the disease, obtained rapid development […]
09 Endocrine drugs Eli Lilly’s Lyumjev is a fast-acting insulin used to improve blood glucose control in adults with type 1 and type 2 diabetes. It was approved in the […]
06 Kidney-urinary system drugs Lupus nephritis is the main cause of morbidity and death in patients with systemic lupus erythematosus (SLE). About 40% of patients with systemic lupus erythematosus will […]
05 Cardiovascular system drugs The sodium-glucose cotransporter 2 (SGLT-2) inhibitor dapagliflozin (Andaton; AstraZeneca) has been on the market as a hypoglycemic agent for nearly 10 years. Another indication of the […]