P53 is a well-known human anticancer protein, known as the guardian of the human genome. Wild-type p53 (WTp53) are widely found in nature. Recently, scientists from the University of California found […]
The US journal Chemical and Chemical News (C&EN) recently published its 2018 Molecular list. These molecules received a lot of attention in 2018. Let’s take a look at these attractive […]
Introduction of EGFR EGFR is the expression product of proto-oncogene C-ERBB1, the receptor of EGF cell proliferation and signal transduction. It is a member of epidermal growth factor receptor (HER) […]
Introduction of JAK-STAT signaling Pathway The JAK-STAT signaling pathway is a signal transduction pathway stimulated by cytokines, which is involved in many important biological processes such as cell proliferation, differentiation, […]
Oxygen heterocyclic ring is one of the most common heterocyclic rings in drugs and natural products. By the end of 2017, 311 drug molecules had at least one oxygen heterocyclic […]
Introduction P53 tumor suppressor gene is a kind of gene that inhibits cells from transforming into cancer cells in living organisms. There are oncogene and tumor suppressor gene in the […]
PI3K is called Phosphatidylinositol 3-kinase (phosphatidylinositol 3-kinase), which is involved in the regulation of various cellular functions such as cell proliferation, differentiation, apoptosis and glucose transport. An increase in PI3K […]
This article takes stock of the latest clinical development pipeline for lung and liver cancer. We calculated clinical trial data for clinical phase Ⅰ, and phase Ⅱ and phase Ⅲ […]
Toll-like receptors (TLRs) are a class of proteins plays an important role in the natural immune system receptor, it was found in the 1990s, a typical pattern recognition receptor (PRR), […]
Inflammation Inflammation is a self-limiting, localized response to any tissue injury or trauma caused by wounding or infection, and is characterized by redness, heat, pain and swelling (rubor, calor, dolor, […]