BOC Sciences Blog

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

p53 target new drug! Aprea’s Blood Cancer Combination Therapy Receives FDA Breakthrough Therapy Designation

Aprea Therapeutics is a Boston-based biopharmaceutical company focused on developing and commercializing innovative cancer therapies that reactivate the tumor suppressor protein p53. Recently, the company announced that the U.S. food […]

When will we find an effective drug for the 2019 novel coronavirus?

When will we find an effective drug for the 2019 novel coronavirus?

Related Products: Remdesivir 2019-nCoV was discovered because of a viral pneumonia case in Wuhan, China in 2019. At present, the 2019-nCoV has shown a very strong ability of human-to-human transmission and […]

The Things You Need to Know about 2019-nCov

The Things You Need to Know about 2019-nCov

Since December 2019, the newly discovered coronavirus (2019-nCov) has caused an outbreak of pneumonia in Wuhan, China, and caused great public concern. At present, the Chinese government has implemented a […]

Dose and Safety of Remdesivir

Dose and Safety of Remdesivir

Related Products: Remdesivir It is reported that Remdesivir has begun a phase III clinical study against new coronavirus (2019-nCoV) at China-Japan Friendship Hospital. Gilead has done a lot of research on […]

Can Remdesivir outwit the 2019 novel coronavirus ?

Can Remdesivir outwit the 2019 novel coronavirus ?

Related Products: Remdesivir In response to the outbreak of pneumonia caused by the new coronavirus, scientific research institutions and pharmaceutical companies around the world are stepping up vaccine research and development […]

Tau protein identified as a key driver of Alzheimer’s disease

Tau protein identified as a key driver of Alzheimer’s disease

In a study published in Science Translational Medicine, a new study by scientists at the center for memory and aging at the University of California, San Francisco (UCSF), shows that […]

New target for Alzheimer’s disease-MSUT2

New target for Alzheimer’s disease-MSUT2

After A string of disappointing clinical trials targeting the amyloid β-protein(Aβ), researchers in the field of Alzheimer’s disease (AD) are paying more attention to the tau protein, another culprit in the disease. Like Aβ, […]

JAA: Oleander may be effective in treating HTLV-1 virus infection

JAA: Oleander may be effective in treating HTLV-1 virus infection

In a new study, researchers from Southern Methodist University and the University of Texas MD Anderson Cancer Center found that oleandrin can stop the spread of HTLV-1 by targeting a […]

Highlights of HIV research in December 2019

Highlights of HIV research in December 2019

Human immunodeficiency virus (HIV), or AIDS (Acquired Immunodeficiency Syndrome) virus, is a virus that causes defects in the human immune system. HIV destroys the body’s T lymphocytes, thereby blocking the […]

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

In a new study, using advances in nanotechnology, researchers have found that restoring p53 not only delays the growth of p53-deficient liver and lung cancer cells, but may also make cancer drugs mTOR inhibitors […]