BOC Sciences Blog

Can Remdesivir outwit the 2019 novel coronavirus ?

Can Remdesivir outwit the 2019 novel coronavirus ?

Related Products: Remdesivir In response to the outbreak of pneumonia caused by the new coronavirus, scientific research institutions and pharmaceutical companies around the world are stepping up vaccine research and development […]

Tau protein identified as a key driver of Alzheimer’s disease

Tau protein identified as a key driver of Alzheimer’s disease

In a study published in Science Translational Medicine, a new study by scientists at the center for memory and aging at the University of California, San Francisco (UCSF), shows that […]

New target for Alzheimer’s disease-MSUT2

New target for Alzheimer’s disease-MSUT2

After A string of disappointing clinical trials targeting the amyloid β-protein(Aβ), researchers in the field of Alzheimer’s disease (AD) are paying more attention to the tau protein, another culprit in the disease. Like Aβ, […]

JAA: Oleander may be effective in treating HTLV-1 virus infection

JAA: Oleander may be effective in treating HTLV-1 virus infection

In a new study, researchers from Southern Methodist University and the University of Texas MD Anderson Cancer Center found that oleandrin can stop the spread of HTLV-1 by targeting a […]

Highlights of HIV research in December 2019

Highlights of HIV research in December 2019

Human immunodeficiency virus (HIV), or AIDS (Acquired Immunodeficiency Syndrome) virus, is a virus that causes defects in the human immune system. HIV destroys the body’s T lymphocytes, thereby blocking the […]

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

Science Translational Medicine: Synthetic mRNA nanoparticle-mediated restoration of p53 tumor suppressor sensitizes p53-deficient cancers to mTOR inhibition

In a new study, using advances in nanotechnology, researchers have found that restoring p53 not only delays the growth of p53-deficient liver and lung cancer cells, but may also make cancer drugs mTOR inhibitors […]

What are the functions of Rapamycin? (II)

What are the functions of Rapamycin? (II)

PLoS Biol: Scientists reveal new mechanism of Rapamycin. doi: 10.1371 / journal.pbio.3000252 Recently, in a research report published in PLoS Biology, scientists from the University of Michigan revealed a new […]

What are the functions of Rapamycin? (I)

What are the functions of Rapamycin? (I)

Rapamycin (RAPA), also known as “sirolimus”, was first discovered by scientists in the soil of Easter Island, Chile in 1975 due to its strong antifungal properties. Rapamycin is a macrolide […]

Durvalumab and Pabolizumab for lung cancer treatment

Durvalumab and Pabolizumab for lung cancer treatment

Small cell lung cancer (SCLC) is a rapidly developing, invasive lung cancer that accounts for about 15% of all lung cancer cases. Among them, about three-quarters of patients with small […]

PROTAC technology: Small molecule drug research and development mass murderer is coming! (Ⅱ)

PROTAC technology: Small molecule drug research and development mass murderer is coming! (Ⅱ)

Protein degradation targeted chimera (PROTAC) PROTAC technology began in 2001 that uses the ubiquitin-proteasome system (UPS), the intracellular “cleaner” for cleaning up denatured, mutated, or harmful proteins in cells. PROTAC, which uses […]