Click chemistry has developed organic reaction methodologies that are rapid, effective, and specifically selective, and its reaction system is not sensitive to oxygen or water. This article first reviews the […]
Lung cancer is a major type of cancer in the world, with the highest morbidity and mortality among all malignant tumors. ALK-positive non-small cell lung cancer (ALK+ NSCLC) is a […]
Distearyl Phthalic Acid Amide, also known as N, N-Stearyl Phthalic Acid Amide or N, N-Tollow Phthalic Acid Amide, is a biodegradable ingredient contained in many cosmetics and personal care products, […]
Drugs targeting HER2 have shown excellent clinical efficacy over the 20 years, achieving one milestone after another in the field of cancer therapeutics. This article mainly introduces the development history […]
Mutations in the epidermal growth factor receptor (EGFR) kinase domain are the oncogenic drivers of this adenocarcinoma. Tyrosine kinase inhibitors (TKIs), developed over the last two decades, targeting EGFR mutations, […]
Why oligonucleotide drugs? Synthetic oligonucleotides are the key factor in almost all molecular biological methodologies. They are used in PCR, reverse transcription, sequencing, gene editing, synthetic biology, cloning, single nucleotide […]
1. Respiratory system 1.1. Lung cancer Drug Name Trade name CAS Target Description Approved Status Gefitinib lressa 184475-35-2 EGFR Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both […]
Fragrances are added in small amounts in the food industry, but can make food more delicious. They are the important source of food flavor and play an important role in […]
In 2007, Japanese professors firstly discovered ALK rearrangement and identified the fusion of ALK and EML4 in non-small cell lung cancer specimens. EML4 can promote the activation of ALK kinase […]
In 2001, the FDA approved Imatinib, the first drug to be developed by targeting a specific protein kinase and the first molecularly targeted drug to fight cancer. It was considered […]