Chemical drugs can be classified into three categories based on their binding modes: covalent drugs, non-covalent drugs, and covalent reversible drugs. Covalent drugs have strong binding ability and high efficacy, […]
Influenza is an acute and highly contagious respiratory disease caused by influenza A and B viruses. Annual influenza epidemics are caused by several different seasonal influenza viruses (i.e., A/H1N1, A/H3N2, B/Yamagata, […]
In recent years, antibody therapies (including traditional antibodies and nano-antibodies) have become an important means of treating a wide range of human malignant diseases, and more than 100 antibody therapies […]
FDA approved the marketing of 14 drugs in the third quarter of 2023, including 6 small molecule drugs. This article mainly focuses on the drug design ideas of small molecule drugs, hoping […]
What is Adjuvants? Adjuvants, also known as immunomodulators or immune enhancers, are an additive to vaccines. Adjuvants are non-specific immune enhancers that enhance or alter the type of immune response […]
Antibody conjugated drug (ADC) is a relatively complex molecule that connects a targeted antibody with a cytotoxic payload through a chemical linker. In recent years, people have gradually deepened their research on payload and […]
RNA-based therapeutics The Human Genome Project (HGP) has revealed a wealth of information about the human genome and has greatly enhanced its role in the development of biomedical research. Thanks […]
In recent years, small nucleic acid drugs have emerged as a focal point in biomedical research due to their strong specificity, simple design, short development cycles, and diverse target options. […]
With the rise of genomics and proteomics, many clinically significant targets have been discovered in human diseases. However, a relatively small proportion of traditional druggable targets exists, and many targets […]
Antibody drug conjugates (ADCs) are multi-domain molecules composed of monoclonal antibodies, linkers and small molecule cytotoxins. ADCs specifically bind target antigens highly expressed on the surface of tumor cells through monoclonal antibodies, enter […]