Zuclopenthixol acetate - CAS 85721-05-7
Catalog number: 85721-05-7
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C24H27ClN2O2S
Molecular Weight:
443.01
COA:
Inquire
Targets:
Dopamine Receptor
Description:
Zuclopenthixol is a typical antipsychotic drug. It belongs to thioxanthene class. Zuclopenthixol is the cis-isomer of clopenthixol. Zuclopenthixol is not approved for use in the United States. It is a dopamine D1/D2 receptor antagonist.It can be use for the treatment of Schizophrenia.
Purity:
98%
Appearance:
Powder
Synonyms:
(Z)-4-(3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl)piperazine-1-ethyl acetate;Clopixol-Acuphase;53772-83-1(base)
Solubility:
Soluble in DMSO
Storage:
-20℃ Freezer
MSDS:
Inquire
Application:
Schizophrenia
Quality Standard:
In-house standard
Shelf Life:
2 month in rt, long time
Quantity:
Milligrams-Grams
Density:
1.266g/cm3
InChIKey:
OXAUOBQMCDIVPQ-IOXNKQMXSA-N
InChI:
1S/C24H27ClN2O2S/c1-18(28)29-16-15-27-13-11-26(12-14-27)10-4-6-20-21-5-2-3-7-23(21)30-24-9-8-19(25)17-22(20)24/h2-3,5-9,17H,4,10-16H2,1H3/b20-6-
Canonical SMILES:
CC(=O)OCCN1CCN(CC1)CC/C=C\2/c3ccccc3Sc4c2cc(cc4)Cl
Current Developer:
Originator Lundbeck
1.Severe laryngeal dystonia in a patient receiving zuclopenthixol "Acuphase" and fluoxetine.
Hood S1, Orr K, Bennett L, Davies S. Australas Psychiatry. 2010 Apr;18(2):174-6. doi: 10.3109/10398560903473686.
OBJECTIVE: Prescribers are warned to be vigilant for potential cytochrome P450 mediated drug interactions; guidelines separately highlight risks of toxicity associated with zuclopenthixol acuphase. We previously examined potential cytochrome P450 interactions with zuclopenthixol and here describe dangerous side effects in a patient receiving zuclopenthixol acuphase and the selective serotonin reuptake inhibitor fluoxetine at high dose.
2.Zuclopenthixol acetate for acute schizophrenia and similar serious mental illnesses.
Jayakody K1, Gibson RC, Kumar A, Gunadasa S. Cochrane Database Syst Rev. 2012 Apr 18;4:CD000525. doi: 10.1002/14651858.CD000525.pub3.
BACKGROUND: Medication used for acute aggression in psychiatry must have rapid onset of effect, low frequency of administration and low levels of adverse effects. Zuclopenthixol acetate is said to have these properties.
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related Dopamine Receptor Products


CAS 854924-64-4 ST 198

ST 198
(CAS: 854924-64-4)

ST 198 is a dopamine D3 receptor antagonist.

CAS 170381-16-5 Zicronapine

Zicronapine
(CAS: 170381-16-5)

Zicronapine, an inden derivative, has been found to be neurotransmitter receptor modulators of sorts of neurotransmitter and was studied against Schizophrenia.

CAS 327026-93-7 Lensiprazine

Lensiprazine
(CAS: 327026-93-7)

Lensiprazine is a potent in vitro dopamine receptor antagonist and highly active as serotonin reuptake inhibitor.

Ecopipam
(CAS: 112108-01-7)

Ecopipam, a synthetic benzazepine derivative drug, acts as a selective dopamine D1/D5 receptor antagonist with little affinity for either dopamine D2-like or 5-...

CAS 146-54-3 Triflupromazine

Triflupromazine
(CAS: 146-54-3)

Triflupromazine, a phenothiazin derivative, has been found to be a D2 dopamine receptor antagonist that could probably used as a tranquilizer and antipsychotic ...

CAS 131796-63-9 Odapipam

Odapipam
(CAS: 131796-63-9)

Odapipam is a potent dopamine D1 antagonist.

CAS 300576-59-4 (+)-PD 128907 hydrochloride

(+)-PD 128907 hydrochloride
(CAS: 300576-59-4)

(+)-PD 128907 hydrochloride, the more active enantiomer of trans-(±)-PD 128907, is a potent D3 dopamine receptor agonist (Ki = 2.3 nM), with 18-200-fold selecti...

CAS 913611-97-9 Brexpiprazole

Brexpiprazole
(CAS: 913611-97-9)

Brexpiprazole, a novel atypical antipsychotic drug, is a D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM). It is approved for the...

Chemical Structure

CAS 85721-05-7 Zuclopenthixol acetate

Quick Inquiry

Verification code

Featured Items