|Targets||5-HT Receptor | Dopamine Receptor|
|Description||Zotepine is a 5-HT2A receptor and dopamine D2 receptor antagonist (Ki = 0.69 and 2.3 nM, respectively) used as an atypical antipsychotic for the treatment of schizophrenia. Zotepine also exhibits an antagonistic effect at histamine H1 receptor (IC50 = 8.0 nM).|
|Brife Description||5-HT2A receptor and dopamine D2 receptor antagonist|
|Purity||≥99% by HPLC|
|Appearance||Off-White to Pale Yellow Solid|
|Synonyms||2-[(8-Chlorodibenzo(Z)[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine; Nipolept; Lodopin; Zoleptil; Zotepina|
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