Zamifenacin fumarate - CAS 127308-98-9
Category: Inhibitor
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Molecular Formula:
C27H29NO3.C4H4O4
Molecular Weight:
531.6
COA:
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Targets:
mAChR
Description:
Zamifenacin fumarate is a selective M3 muscarinic receptor antagonist (pKi = 8.52, 7.93, 7.90 and 7.78 for M3, M2, M1 and M4 receptors, respectively). Zamifenacin fumarate exhibits higher affinity for ileal M3 receptors (pKi = 9.3) than oesophageal and tracheal M3 receptors (pKi = 8.8 and 8.2 respectively).
Brife Description:
muscarinic M3 receptor antagonist
Purity:
≥99% by HPLC
Related CAS:
127308-82-1 (free base)
Synonyms:
(3R)-1-[2-(1-,3-Benzodioxol-5-yl)ethyl]-3-(diphenylmethoxy)piperidine fumarate
MSDS:
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InChIKey:
PMHKTAIGYOVZEZ-ZHWJIHCSSA-N
InChI:
InChI=1S/C27H29NO3.C4H4O4/c1-3-8-22(9-4-1)27(23-10-5-2-6-11-23)31-24-12-7-16-28(19-24)17-15-21-13-14-25-26(18-21)30-20-29-25;5-3(6)1-2-4(7)8/h1-6,8-11,13-14,18,24,27H,7,12,15-17,19-20H2;1-2H,(H,5,6)(H,7,8)/b;2-1+/t24-;/m1./s1
Canonical SMILES:
C1CC(CN(C1)CCC2=CC3=C(C=C2)OCO3)OC(C4=CC=CC=C4)C5=CC=CC=C5.C(=CC(=O)O)C(=O)O
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Chemical Structure

CAS 127308-98-9 Zamifenacin fumarate

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