XAV939 - CAS 284028-89-3
Catalog number: 284028-89-3
Not Intended for Therapeutic Use. For research use only.
Molecular Formula:
C14H11F3N2OS
Molecular Weight:
312.31
COA:
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Description:
XAV939 is a cell-permeable small molecule inhibitor of the Wnt / β-catenin pathway. XAV939 inhibits tankyrase 1 and tankyrase 2, thus stabilizing axin and stimulating β-catenin degradation. Current research suggests that Wnt proteins act to maintain stem cells in an undifferentiated, self-renewing state. Wnt proteins act on a variety of stem cells that include neural, mammary and embryonic stem cells. In addition, XAV939 inhibits growth of DLD-1 cells, an APC-deficient colorectal cancer cell line.
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Purity:
0.98
Appearance:
White powder
MSDS:
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Application:
Differentiation
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CAS 284028-89-3 XAV939

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