WAY 262611 dihydrochloride
Category: Inhibitor
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Molecular Formula:
Molecular Weight:
Wnt | β-catenin
WAY 262611 dihydrochloride is an inhibitor of Dickkopf-1 (DKK1), which antagonizes Wnt/β-Catenin signaling. DKK1 is a soluble inhibitor of Wnt-3a mediated Wnt/β-catenin signaling required for embryonic head development. Inhibition of DKK1 by WAY 262611 activates the Wnt signaling pathway and stimulates β-catenin/TCF-dependent transcription with an EC50 value of 0.63 µM.
Brife Description:
Dickkopf-1 (DKK1) inhibitor
WAY-262611 dihydrochloride; WAY 262611 dihydrochloride; WAY262611 dihydrochloride; (1-(4-(naphthalen-2-yl)pyrimidin-2-yl)piperidin-4-yl)methanamine dihydrochloride
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