VUF 10166 - CAS 155584-74-0
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
5-HT Receptor
VUF 10166 is a potent and competitive 5-HT3 receptor antagonist (IC50 = 0.04 and 22 nM for human 5HT3A and 5-HT3AB receptors, respectively). VUF 10166 exhibits partial agonist activity at 5-HT3A receptors at higher concentrations (EC50 = 5.2 μM). It also acts as a histamine H4 receptor antagonist (pKi = 6.64 in HEK cells).
Brife Description:
5-HT3 receptor antagonist
≥98% by HPLC
VUF 10166; VUF10166; VUF-10166; 2-Chloro-3-(4-methyl-1-piperazinyl)quinoxaline
Canonical SMILES:
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related 5-HT Receptor Products

CAS 1331782-27-4 PF-04995274

(CAS: 1331782-27-4)

PF-04995274 is a 5-HT4 receptor partial agonist with Ki = 0.15 - 0.46 nM for 5-HT4 isoforms a, b, d and e, developed for the treatment of Alzheimer's disease (A...

CAS 157798-13-5 5-Nonyloxytryptamine oxalate

5-Nonyloxytryptamine oxalate
(CAS: 157798-13-5)

5-Nonyloxytryptamine oxalate is a potent agonist of the serotonin (5-HT) receptor 5-HT1Dβ with an EC50 value of 68 nM for adenylate cyclase activity in CHOKM6 c...

CAS 144734-36-1 4F 4PP oxalate

4F 4PP oxalate
(CAS: 144734-36-1)

4F 4PP oxalate is a selective 5-HT2A antagonist with almost as high affinity (Ki = 5.3 nM) as ketanserin but with a much lower affinity for 5-HT2C sites (Ki = 6...

CAS 1217674-10-6 SB 258719 hydrochloride

SB 258719 hydrochloride
(CAS: 1217674-10-6)

SB 258719 hydrochloride is a selective 5-HT7 receptor antagonist, displaying > 100-fold selectivity over a range of other receptors. SB 258719 shows inverse act...

CAS 85181-40-4 Tropanyl-3,5-dimethylbenzoate

(CAS: 85181-40-4)

Tropanyl-3,5-dimethylbenzoate is a 5-HT3 receptor antagonist.

CAS 132907-72-3 Ramosetron Hydrochloride

Ramosetron Hydrochloride
(CAS: 132907-72-3)

The hydrochloride salt form of Ramosetron, a benzimidazol derivative, could be used to against nausea and vomiting for acting as a 5-HT3 receptor antagonist.

CAS 866206-54-4 PRX 08066

PRX 08066
(CAS: 866206-54-4)

PRX 08066, a selective 5-hydroxytryptamine receptor 2B(5-HT2BR) antagonist, causes selective vasodilation of pulmonary arteries. Its IC50 value is 3.4 nM. It ca...

CAS 187665-65-2 PNU 142633

PNU 142633
(CAS: 187665-65-2)

PNU 142633 is a selective, high affinity 5-HT1D receptor antagonist (Ki values are 6 and > 18000 nM at human 5-HT1D and 5-HT1B receptors respectively). It is an...

Chemical Structure

CAS 155584-74-0 VUF 10166

Quick Inquiry

Verification code

Featured Items