|Description||VU 0422288 is a group III mGlu receptor positive allosteric modulator (EC50 = 108, 125 and 146 nM for mGlu4, mGlu8 and mGlu7, respectively) with selectivity over a panel of 68 other GPCRs, ion channels and transporters. VU 0422288 has been shown to potentiate mGlu7-mediated reductions in excitatory post synaptic potentials in hippocampal slices.|
|Brife Description||group III mGluR positive allosteric modulator|
|Purity||≥98% by HPLC|
|Synonyms||VU0422288; VU-0422288; VU 0422288; ML 396; ML-396; ML396; N-[3-Chloro-4-[(5-chloro-2-pyridinyl)oxy]phenyl]-2-pyridinecarboxamide|
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CHPG Sodium salt
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