VU 0409106 - CAS 1276617-62-9
Category: Inhibitor
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Molecular Formula:
C15H11FN4O2S
Molecular Weight:
330.34
COA:
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Targets:
mGluR
Description:
VU 0409106 is a potent and selective mGlu5 negative allosteric modulator (IC50 = 49 nM for human mGlu5) with selectivity over a panel of GPCRs and ion channels. VU 0409106 exhibits no significant nonspecific binding in rat brain homogenates in vitro.
Brife Description:
mGlu5 negative allosteric modulator
Purity:
≥98% by HPLC
Synonyms:
VU0409106, VU 0409106, VU-0409106; 3-Fluoro-N-(4-methyl-2-thiazolyl)-5-(5-pyrimidinyloxy)benzamide
MSDS:
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InChIKey:
AXVLPJHYYFHCHK-UHFFFAOYSA-N
InChI:
InChI=1S/C15H11FN4O2S/c1-9-7-23-15(19-9)20-14(21)10-2-11(16)4-12(3-10)22-13-5-17-8-18-6-13/h2-8H,1H3,(H,19,20,21)
Canonical SMILES:
CC1=CSC(=N1)NC(=O)C2=CC(=CC(=C2)F)OC3=CN=CN=C3
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Chemical Structure

CAS 1276617-62-9 VU 0409106

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