VU 0155041 - CAS 1093757-42-6
Category: Inhibitor
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Molecular Formula:
Molecular Weight:
VU 0155041 is a potent positive allosteric modulator at mGlu4 receptors (EC50 = 798 and 693 nM at human and rat mGlu4 receptors, respectively). VU 0155041 displays no activity for 67 G protein-coupled receptors, ion channels, and transporters, and lacks antagonist activity at NMDA receptors in striatal medium spiny neurons at a concentration of 10 μM. VU 0155041 is active in in vivo models of Parkinson's disease following i.c.v. administration.
Brife Description:
positive allosteric modulator at mGlu4 receptors
≥99% by HPLC
Related CAS:
1259372-69-4 (sodium salt)
VU0155041, VU 0155041, VU-0155041; cis-2-[[(3,5-Dichlorophenyl)amino]carbonyl]cyclohexanecarboxylic acid; (1R,2S)-2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylic acid
Canonical SMILES:
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Chemical Structure

CAS 1093757-42-6 VU 0155041

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