|Description||Venetoclax is a small-molecule inhibitor that has high selectivity for Bcl-2 (Ki < 0.01 nM in cell-free assays) over Mcl-1. It suppresses anti-apoptotic Bcl-2, a protein commonly overexpressed in cancer cells, to induce programmed death of CLL cells. Venetoclax is used as a second-line treatment of chronic lymphocytic leukemia (CLL).|
|B0084-462638||500 mg||$298||In stock|
|Brife Description||Bcl-2 inhibitor, chronic lymphocytic leukemia (CLL)|
|Synonyms||ABT199; ABT-199; ABT 199; GDC0199; GDC0199; GDC 0199; RG7601; RG7601; RG 7601. Venetoclax|
|Solubility||10mM in DMSO|
|Application||the treatment of chronic lymphocytic leukemia (CLL)|
|Shelf Life||2 years|
|Current Developer||AbbVie; Genentech|
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