VBY-825 - CAS 1310340-58-9
Catalog number: 1310340-58-9
Category: Inhibitor
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Molecular Formula:
C23H29F4N3O5S
Molecular Weight:
535.55
COA:
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Targets:
Cathepsin
Description:
VBY-825 is a potent inhibitor of the assayed cathepsins and its potency against at least one cathepsin, cathepsin S, extends across species relevant for pharmacology studies, specifically mouse. 10 mg/kg/day dose of VBY-825 achieves a trough plasma concentration >200nM, which is well above that required for full inhibition of the intracellular activity of cathepsins B, F, K, L, S and V in both mouse and human cell lines.
Purity:
>98%
Synonyms:
VBY-825; VBY 825; VBY825
MSDS:
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InChIKey:
PPUXXDKQNAHHON-BJLQDIEVSA-N
InChI:
InChI=1S/C23H29F4N3O5S/c1-2-17(19(31)22(33)28-16-9-10-16)30-21(32)18(12-36(34,35)11-13-3-4-13)29-20(23(25,26)27)14-5-7-15(24)8-6-14/h5-8,13,16-18,20,29H,2-4,9-12H2,1H3,(H,28,33)(H,30,32)/t17-,18-,20-/m0/s1
Canonical SMILES:
CCC(C(=O)C(=O)NC1CC1)NC(=O)C(CS(=O)(=O)CC2CC2)NC(C3=CC=C(C=C3)F)C(F)(F)F
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CAS 1310340-58-9 VBY-825

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