|Description||Vaborbactam is a selective beta-lactamase inhibitor under the development of Rempex Pharmaceuticals. Vaborbactam is a broad-spectrum inhibitor, especially restoring the activity of carbapenems against KPC-producing strains. Combined with a carbapenem, Vaborbactam can be a promising product for the treatment of multidrug resistant Gram-negative bacteria. Phase III clinical trials for the treatment of Bacteraemia, Gram-negative infections, Pneumonia, Pyelonephritis and Urinary tract infections are on-going.|
|Synonyms||RPX 7009; MP-7009; REBO-07; MP-7;Meropenem;2-((3R,6S)-2-hydroxy-3-(2-(thiophen-2-yl)acetamido)-1,2-oxaborinan-6-yl)acetic acid|
|Solubility||Soluble in DMSO|
|Application||Bacteraemia, Gram-negative infections, Pneumonia, Pyelonephritis and Urinary tract infections|
|Quality Standard||In-house standard|
|Shelf Life||2 month in rt, long time|
|Current Developer||Rempex Pharmaceuticals; The Medicines Company; US Department of Health and Human Services|
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