UNC 3230 - CAS 1031602-63-7
Category: Inhibitor
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Molecular Formula:
C17H20N4O2S
Molecular Weight:
344.43
COA:
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Targets:
Others
Description:
UNC 3230 is a potent and selective PIP5K1C inhibitor (IC50 = 41 nM), displaying selectivity for PIP5K1C over PIP5K1A, the PI 3-kinase family and a panel of other kinases. UNC 3230 decreases PIP2 levels and LPA-induced calcium signaling in dorsal root ganglia (DRG) neurons in vitro. UNC 3230 exhibits antinociceptive effects in mouse models of chronic pain.
Brife Description:
PIP5K1C inhibitor
Purity:
≥99% by HPLC
Synonyms:
UNC3230; UNC-3230; UNC 3230; 5-[(Cyclohexylcarbonyl)amino]-2-(phenylamino)-thiazolecarboxamide
MSDS:
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InChIKey:
RZCNASHHHSKTGP-UHFFFAOYSA-N
InChI:
InChI=1S/C17H20N4O2S/c18-14(22)13-16(21-15(23)11-7-3-1-4-8-11)24-17(20-13)19-12-9-5-2-6-10-12/h2,5-6,9-11H,1,3-4,7-8H2,(H2,18,22)(H,19,20)(H,21,23)
Canonical SMILES:
C1CCC(CC1)C(=O)NC2=C(N=C(S2)NC3=CC=CC=C3)C(=O)N
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CAS 1031602-63-7 UNC 3230

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