(+)-UH 232 maleate - CAS 1217473-50-1
Category: Inhibitor
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Molecular Formula:
C18H29NO.C4H4O4
Molecular Weight:
391.51
COA:
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Targets:
Dopamine Receptor
Description:
(+)-UH 232 maleate is a dopamine D2 antagonist (Ki = 72.7 nM in a ligand binding assay; apparent KB = 14.5 nM in a cAMP accumulation assay) that preferentially effects on central dopamine autoreceptors. (+)-UH 232 maleate significantly promotes dopamine synthesis and turnover. (+)-UH 232 maleate is also a dopamine D3 partial agonist.
Brife Description:
dopamine D2 antagonist
Synonyms:
cis-(+)-5-Methoxy-1-methyl-2-(di-N-propylamino)tetralin maleate; SR-01000597860
MSDS:
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InChIKey:
MEQAJDYHKYAPJE-GUUGRXDUSA-N
InChI:
InChI=1S/C18H29NO.C4H4O4/c1-5-12-19(13-6-2)17-11-10-16-15(14(17)3)8-7-9-18(16)20-4;5-3(6)1-2-4(7)8/h7-9,14,17H,5-6,10-13H2,1-4H3;1-2H,(H,5,6)(H,7,8)/b;2-1-/t14-,17+;/m0./s1
Canonical SMILES:
CCCN(CCC)C1CCC2=C(C1C)C=CC=C2OC.C(=CC(=O)O)C(=O)O
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Chemical Structure

CAS 1217473-50-1 (+)-UH 232 maleate

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