UCN-01 - CAS 112953-11-4
Catalog number: 112953-11-4
Category: Metabolites
Molecular Formula:
C28H26N4O4
Molecular Weight:
482.5
COA:
Inquire
source\Analogue Sets:
Streptomyces
Description:
An indolocarbazole isolated from a high staurosporine-producing streptomyces culture; inhibits protein kinase C (PKC) and cyclin-dependant kinase 2 (CDK2), resulting in accumulation of cells in the G1 phase and induction of apoptosis; also enhances the cytotoxicity of other anti-cancer drugs, such as DNA-damaging agents and anti-metabolite drugs, through putative abrogation of G2 and/or S phase accumulation induced by the latter agents.
Purity:
>99% by HPLC
Appearance:
White Film
Synonyms:
7-Hydroxystaurosporine
Solubility:
Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Storage:
-20°C
MSDS:
Inquire
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CAS 112953-11-4 UCN-01

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