|Description||Trequinsin hydrochloride is a highly potent inhibitor of cGMP-inhibited phosphodiesterase (PDE3) (IC50 = 250 pM). Trequinsin stimulates cAMP accumulation at a concentration of 10 µM, and inhibits arachidonic acid-induced platelet aggregation (IC50 = 50 pM). Trequinsin was shown to decrease blood pressure levels in both normotensive and hypertensive animal models and is used as an antihypertensive agent.|
|Brife Description||PDE3 inhibitor|
|Purity||≥97% by HPLC|
|Related CAS||79855-88-2 (free base)|
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