Tranexamic Acid - CAS 1197-18-8
Catalog number: 1197-18-8
Category: Inhibitor
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Molecular Formula:
C8H15NO2
Molecular Weight:
157.21
COA:
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Targets:
Others
Description:
Tranexamic Acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.
Purity:
>98%
Synonyms:
Tranexamic Acid, TXA, Trans AMCHA, Cyklokapron
MSDS:
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InChIKey:
GYDJEQRTZSCIOI-UHFFFAOYSA-N
InChI:
InChI=1S/C8H15NO2/c9-5-6-1-3-7(4-2-6)8(10)11/h6-7H,1-5,9H2,(H,10,11)
Canonical SMILES:
C1CC(CCC1CN)C(=O)O
1.Oral surgery in liver transplant candidates: a retrospective study on delayed bleeding and other complications.
Helenius-Hietala J1, Åberg F2, Meurman JH3, Nordin A4, Isoniemi H4. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016 May;121(5):490-5. doi: 10.1016/j.oooo.2016.01.025. Epub 2016 Feb 13.
OBJECTIVE: Untreated dental infections pose a threat for immunocompromised liver transplant (LT) recipients. Therefore, pretransplant dental evaluations are recommended. However, risk of bleeding should be considered among patients with end-stage liver disease, and prophylactic blood transfusions may be used to prevent bleeding. We performed a retrospective study of the incidence of and risk factors for oral surgery-related bleeding in candidates for LT and hypothesized that complications may occur despite preoperative and perioperative hemostatic actions.
2.Intravenous tranexamic acid for hyperacute primary intracerebral hemorrhage: Protocol for a randomized, placebo-controlled trial.
Sprigg N1, Robson K2, Bath P2, Dineen R2, Roberts I2, Robinson T2, Roffe C2, Werring D2, Al-Shahi Salman R2, Pocock S2, Duley L2, England T2, Whynes D2, Ciccone A2, Laska AC2, Christensen H2, Ozturk S2, Collins R2, Bereczki D2, Egea-Guerrero JJ2, Law ZK2, Int J Stroke. 2016 Apr 5. pii: 1747493016641960. [Epub ahead of print]
RATIONALE: Outcome after intracerebral hemorrhage remains poor. Tranexamic acid is easy to administer, readily available, inexpensive, and effective in other hemorrhagic conditions.
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CAS 1197-18-8 Tranexamic Acid

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