Topotecan - CAS 123948-87-8
Category: ADCs
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C23H23N3O5
Molecular Weight:
421.45
COA:
Inquire
Tag:
ADCs Cytotoxin
Description:
Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells.
Purity:
≥95%
Appearance:
Soild powder
Synonyms:
(S)-10-((dimethylamino)methyl)-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione hydrochloride;Hycamtin; SKF104864;
MSDS:
Inquire
InChIKey:
UCFGDBYHRUNTLO-QHCPKHFHSA-N
InChI:
InChI=1S/C23H23N3O5/c1-4-23(30)16-8-18-20-12(9-26(18)21(28)15(16)11-31-22(23)29)7-13-14(10-25(2)3)19(27)6-5-17(13)24-20/h5-8,27,30H,4,9-11H2,1-3H3/t23-/m0/s1
Canonical SMILES:
CC[C@@]1(c2cc3n(c(=O)c2COC1=O)Cc4c3nc5ccc(c(c5c4)CN(C)C)O)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related ADCs Cytotoxin Products


Aldoxorubicin hydrochloride
(CAS: 480998-12-7)

Aldoxorubicin is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic activity.

CAS 515-25-3 Betonicine

Betonicine
(CAS: 515-25-3)

Is any neutral chemical compound with a positively charged cationic functional group such as a quaternary ammonium or phosphonium cation which bears no hydrogen...

CAS 26000-17-9 Lycoctonine

Lycoctonine
(CAS: 26000-17-9)

Lycoctonine is a plant alkaloid and a precursor to the ABC ring system of taxoids.

CAS 19918-85-5 Diplacine

Diplacine
(CAS: 19918-85-5)

Diplacine is a nicotinic cholinoreceptor antagonist at the neuromuscular junction.

FSP-2

Anticoagulant: irreversible inhibitor of serine proteinase a-thrombine. Fluorocontaining phosphonate, synthetised.

CAS 60-38-8 3-Acetyl-Strophanthidin

3-Acetyl-Strophanthidin
(CAS: 60-38-8)

An ATPase inhibitor.

Cardiotoxin
(CAS: 56574-47-1)

A cytolytic toxin that causes depolarization of skeletal muscle fibers in vitro. Stimulates Ca2+ transport and ATP hydrolysis by the sarcolemmal Ca2+/Mg2+-ATPas...

CAS 23541-50-6 Daunorubicin Hydrochloride

Daunorubicin Hydrochloride
(CAS: 23541-50-6)

Daunorubicin Hcl inhibits both DNA and RNA synthesis and inhibits DNA synthesis with Ki of 0.02 μM.

Chemical Structure

CAS 123948-87-8 Topotecan

Quick Inquiry

Verification code

Featured Items