Timosaponin A1 - CAS 68422-00-4
Catalog number: B0005-479868
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C33H54O8
Molecular Weight:
578.78
COA:
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Chemical Family:
Other Natural Compounds
Description:
Timosaponin A1 a coprostane type steroidal saponin isolated from Rhizoma Anemarrhenae which is the dry rootstock of Anemarrhenae asphodeloides Bunge (Liliaceae) dug in spring and fall. The rhizome of Anemarrhena asphodeloides Bunge (Liliaceae), has been used for a long time in traditional Chinese medicine with anti-diabetic activity anti-platelet aggregation activity and diuretic activity.
Ordering Information
Catalog Number Size Price Stock Quantity
B0005-479868 20mg $399 In stock
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Purity:
> 98%
Appearance:
White solid powder
Synonyms:
(3β,5β,25S)-Spirostan-3-yl β-D-galactopyranoside; β-​D-​Galactopyranoside, (3β,​5β,​25S)​-​spirostan-​3-​yl; Sarsasapogenin, β-D-galactopyranoside (7CI)
Solubility:
Soluble in DMSO
Storage:
Store in a cool and dry place and at 0 - 4℃ for short term (days to weeks) or -42℃ for long term (months to years).
MSDS:
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Quality Standard:
Enterprise Standard
Quantity:
Milligrams-Grams
Boiling Point:
1.26±0.1 g/cm3 | Condition: Temp: 20 °C Press: 760 Torr
Density:
1.26±0.1 g/cm3
1.Identification and analysis of chemical constituents and rat serum metabolites in Suan-Zao-Ren granule using ultra high performance liquid chromatography quadrupole time-of-flight mass spectrometry combined with multiple data processing approaches.
Du Y;He B;Li Q;He J;Wang D;Bi K J Sep Sci. 2017 Jul;40(14):2914-2924. doi: 10.1002/jssc.201700236. Epub 2017 Jun 20.
Suan-Zao-Ren granule is widely used to treat insomnia in China. However, because of the complexity and diversity of the chemical compositions in traditional Chinese medicine formula, the comprehensive analysis of constituents in vitro and in vivo is rather difficult. In our study, an ultra high performance liquid chromatography with quadrupole time-of-flight mass spectrometry and the PeakView® software, which uses multiple data processing approaches including product ion filter, neutral loss filter, and mass defect filter, method was developed to characterize the ingredients and rat serum metabolites in Suan-Zao-Ren granule. A total of 101 constituents were detected in vitro. Under the same analysis conditions, 68 constituents were characterized in rat serum, including 35 prototype components and 33 metabolites. The metabolic pathways of main components were also illustrated. Among them, the metabolic pathways of timosaponin AI were firstly revealed. The bioactive compounds mainly underwent the phase I metabolic pathways including hydroxylation, oxidation, hydrolysis, and phase II metabolic pathways including sulfate conjugation, glucuronide conjugation, cysteine conjugation, acetycysteine conjugation, and glutathione conjugation.
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CAS 68422-00-4 Timosaponin A1

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