Ticagrelor - CAS 274693-27-5
Catalog number: B0084-089156
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
Molecular Weight:
P2Y Receptor
Ticagrelor, the first reversible oral P2Y12 receptor antagonist, provides faster, greater, and more consistent ADP-receptor inhibition than Clopidogrel. Used in the treatment of acute coronary syndromes (ACS).
Ordering Information
Catalog Number Size Price Stock Quantity
B0084-089156 1 g $169 In stock
Bulk Inquiry
White to Off-White Solid
AZD-6140; AZD6140; AZD 6140; AR-C 126532XX; AR-C-126532XX; AR-C126532XX; Ticagrelor; brand name: Brilinta; Brilique; Possia
Canonical SMILES:
1.Efficacy and Safety of Ticagrelor as Long-Term Secondary Prevention in Patients with Peripheral Artery Disease and Prior Myocardial Infarction.
Bonaca MP1, Bhatt DL2, Storey RF3, Steg PG4, Cohen M5, Kuder J2, Goodrich E2, Nicolau JC6, Parkhomenko A7, López-Sendón J8, Dellborg M9, Dalby A10, Špinar J11, Aylward P12, Corbalán R13, Abola MT14, Jensen EC15, Held P15, Braunwald E2, Sabatine MS2. J Am Coll Cardiol. 2016 Mar 28. pii: S0735-1097(16)32403-2. doi: 10.1016/j.jacc.2016.03.524. [Epub ahead of print]
BACKGROUND: Peripheral artery disease (PAD) has been associated with heightened ischemic and bleeding risk in patients with prior myocardial infarction (MI).
2.Ticagrelor Attenuates Apoptosis of Lung and Myocardial Cells Induced by Abdominal Aorta Ischemia/Reperfusion.
Findik O1, Kunt AT1, Yazir Y2, Yardimoğlu M2, Yilmaz SG3, Aydin U4, Rençber SF2, Baris O1, Balci C5, Isbir T6. In Vivo. 2016 05-06;30(3):243-249.
AIM: This study aimed to analyze the effect of ticagrelor pretreatment on the prevention of lung and heart injury induced by abdominal aorta ischemia and reperfusion (I/R) and also to determine the effective dose.
3.Pharmacodynamics, pharmacokinetics, and safety of ticagrelor in Chinese patients with stable coronary artery disease.
Li H1, Guo J1, Carlson GF2, Teng R2. Br J Clin Pharmacol. 2016 Apr 1. doi: 10.1111/bcp.12950. [Epub ahead of print]
AIMS: To assess ticagrelor's effects on inhibition of platelet aggregation (IPA), P2Y12 reaction units (PRU; measure of platelet P2Y12 receptor blockade), pharmacokinetic (PK) parameters and safety in Chinese patients with stable coronary artery disease (CAD).
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related P2Y Receptor Products

CAS 202982-98-7 NF 340

NF 340
(CAS: 202982-98-7)

NF 340 is a selective P2Y11 antagonist. It shows competitive antagonism against ATPγS with pIC50 values of 6.43 and 7.14 in Ca2+ and cAMP assays respectively.

CAS 1047980-83-5 MRS 2768 tetrasodium salt

MRS 2768 tetrasodium salt
(CAS: 1047980-83-5)

MRS 2768 tetrasodium salt is a selective P2Y2 agonist (EC50 = 1.89 μM), with no affinity for human P2Y4 or P2Y6 receptors.

(CAS: 110505-75-4)

N6-(4-Hydroxybenzyl)adenosine, an imidazopyrimidine derivative, could be effective as an inhibitor of platelet aggregation. IC50: 6.77-141 μM.

CAS 145-63-1 Suramin

(CAS: 145-63-1)

Suramin, also called as Germanin, has been demonstrated to inhibit a large variety of enzymes including urease, hexokinase, succinic dehydrogenase, p-glucuronid...

CAS 1006028-37-0 NF 546

NF 546
(CAS: 1006028-37-0)

NF 546 is a P2Y11 agonist with pEC50 value of 6.27. It can stimulate release of interleukin-8 from human monocyte-derived dendritic cells.

CAS 163706-06-7 Cangrelor

(CAS: 163706-06-7)

Cangrelor, an adenylic acid derivative, has been found to be a P2Y12 inhibitor that could be effective in some coronary artery diseases. It is under Phase I tri...

CAS 163706-36-3 Cangrelor tetrasodium

Cangrelor tetrasodium
(CAS: 163706-36-3)

Cangrelor tetrasodium is an ATP analogue and acts as a reversible antagonist of P2Y12 receptor. Pretreatment with cangrelor significantly reduces blood clotting...

CAS 129-46-4 Suramin Sodium

Suramin Sodium
(CAS: 129-46-4)

The sodium salt of Suramin which is a P2 purinergic antagonist and has been also found to have the effect in blocking the G protein binds to GPCRs so that it wa...

Chemical Structure

CAS 274693-27-5 Ticagrelor

Quick Inquiry

Verification code

Featured Items