|Description||Thiocolchicoside is a semi-synthetic derivative of colchicine, an anti-inflammatory glycoside extracted from the flower seeds of superba gloriosa. Thiocolchicoside acts as a GABAA receptor antagonist exhibiting anti-inflammatory and analgesic activity. It is used as a muscle relaxant.|
|B0084-464811||500 mg||$199||In stock|
|B0084-464811||1 g||$299||In stock|
|Brife Description||GABAA receptor antagonist|
|Synonyms||N-[(7S)-3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; (S)-N-[3-(β-D-Glucopyranosyloxy)-5,6,7,9-tetrahydro-1,2-dimethoxy-10-(methylthio)-9-oxobenzo[a]heptalen-7-yl]acetamide; Coltramyl; Coltrax; Miorel; Miotens; Muscoril|
|Storage||Store at -20°C|
|Melting Point||>197°C (dec.)|
CL 218872 has been found to be a benzodiazepine agonist and has been found to exhibit anxiolytic and anticonvulsant activities.
A GABAA receptor modulator that effects against anxiety.
CGP7930 is a positive allosteric modulator at the GABAB receptor. It has anxiolytic effects in animal studies, and has a synergistic effect with GABAB agonists ...
SCS is a potent and selective partial inhibitor of β1-containing GABAA receptors (IC50 = 4.5, 5.3 and 7.9 nM at α2β1γ1θ, α2β1γ1 and α2β1γ2s GABAA receptors, res...
Arbaclofen, the R-enantiomer of baclofen, is a selective gamma-amino butyric acid type B receptor agonist used for autism spectrum disorder and fragile X syndro...
Isoguvacine hydrochloride is a selective GABA receptor agonist with anticonvulsant and antiepileptic effect, developed for Neuroscience research.
CGS 20625 is a partial agonist for the benzodiazepine binding site of the GABAA receptor used as an anti-anxiety drug. It acts as a central benzodiazepine recep...
Primidone, a pyrimidinedione derivative, could be used as an anticonvulsant agent especially against epilepsy unspecified.
3-Methyl-GABA is an activator of GABA aminotransferase.
Pagoclone, an active (+)-enantiomer of the racemate RP 59037, is a ubtype selective partial agonist at GABAA receptor and used for the treatment of panic and an...
Lorediplon is a hypnotic drug acting as a GABAA receptor modulator, differentially active at the alpha1-subunit. It is a novel nonbenzodiazepine of the pyrazolo...
L-655,708, an inverse agonist of α5 subunit involved in GABAA receptor, has been found to exhibit cognitive performance improvement in biological studies.
Etifoxine Hydrochloride is Potentiator of GABAA receptor with anxiolytic and anticonvulsant activity.
CGP 13501 is a positive allosteric modulator of GABAB receptors, potentiating the effects of GABA at this receptor type.
Etomidate hydrochloride is a GABAA receptor agonist used for the induction of general anaesthesia.
MRK-016 is a selective α5 subunit-containing GABAA negative allosteric modulator with EC50 value of 3 nM. It has nootropic properties. MRK-016 can produce rapid...
This active molecular is a highly selective inverse agonist/negative allosteric modulator GABAAα5 receptors. It was developed by Roche to treat cognitive impair...
Baclofen, an agonist of GABAB receptor, could be effective as a skeletal muscle relaxant and has been also found to have antispastic effect.
U 89843A is a positive allosteric modulator of GABAA receptors. U 89843A potentiates GABA-induced Cl- currents in the α1β2γ2, α3β2γ2 and α6β2γ2 GABAA receptors....
AA 29504 is a positive allosteric modulator of GABAA receptors with anxiolytic activity. It modulates both α4β3δ-containing extrasynaptic receptors and α1β3γ2S-...