|Description||Tetrabenazine is a VMAT-inhibitor used for treatment of hyperkinetic movement disorder. It is a monoamine-depleting and a dopamine-receptor-blocking drug and is an effective and safe drug for the treatment of a variety of hyperkinetic movement disorders.|
Tautomycetin is a selective inhibitor of protein phosphatase (PP)1 (IC50 = 1.6 and 62 nM for PP1 and PP2, respectively) used as an immunosuppressive agent. Taut...
Cycloastragenol is a natural tetracyclic triterpenoid. It is an aglycone derivative of astragaloside IV found in the root of Korean Astragalus membranaceus. It ...
Nobiletin, a citrus flavonoid isolated from citrus peels like in tangerine, which has anti-inflammatory and anti-tumor activities.
FR-182024, an azabicyclo derivative, has been found to have potential activity as an anti-Helicobacter pylori agent and was once stuied against helicobacter inf...
Acarbose is an inhibitor of intestinal alpha-glucosidase, used to treat type 2 diabetes mellitus.
Pseudoginsenoside- F11 is extracted from the roots of Panax ginseng C. A. Mey, has been demonstrated to antagonize the learning and memory deficits induced by s...
Uridine is a nucleoside, contains a uracil attached to a ribose ring via a β-N1-glycosidic bond.
SV40 large T antigen NLS, a hexamer protein generated from Large T antigen residue 47 to 55, enables protein import into cell nucleus.
The hydrochloride salt form of KHK-IN-1 which is a ketohexokinase inhibitor that could have probable effect against diabetes and obesity by acting on Asp-27B in...
JTP-4819, a pyrrolidine derivative, has been found to be a PEP inhibitor that was once studied in cognition disorders and had been already been discontinued.
Bufotalin is a cardiotoxic bufanolide steroid, cardiac glycoside analogue, secreted by a number of toad species. It is a novel anti-osteoblastoma agent.
Nanterinone is a novel positive inotropic and balanced-type vasodilating drug partially based on phosphodiesterase III inhibition. It exhibits acute hemodynamic...
Chlorambucil (marketed as Leukeran by GlaxoSmithKline) is a chemotherapy drug that has been mainly used in the treatment of chronic lymphocytic leukemia. It is ...
Oxytocin is a mammalian neurohypophysial hormone. It plays an important role in the neuroanatomy of intimacy, specifically in sexual reproduction of both sexes,...
ENT 25642, a sulfamide derivative, could have potential activities in sorts of biological studies.
CP-69799 is an inhibitor of aspartate proteinases.
HL 010183 is a metformin derivative exhibiting potent antitumor effect. It inhibits proliferation and invasion of Hs578T triple-negative (TN) breast cancer cell...
N3PT inhibits transketolase activity in a cell based assay. Competitive inhibition of TK by N3PT in cells treated with increasing doses of thiamine, expressed a...
Bromhexine is a mucolytic (expectorant) agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine ...
GSK-1268992 is one of a metabolite of Pazopanib which is a selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits an...