TCS 1205 - CAS 355022-97-8
Category: Inhibitor
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Molecular Formula:
C18H15N3O4
Molecular Weight:
337.33
COA:
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Targets:
GABA Receptor
Description:
TCS 1205 is a GABAA α2 benzodiazepine receptor agonist and GABAA α1 partial agonist in vitro (Ki = 14 and 121 nM, respectively). It displays non-sedative anxiolytic activity in vivo.
Brife Description:
α2 benzodiazepine receptor agonist, α1 benzodiazepine receptor partial agonist
Purity:
≥99% by HPLC
Synonyms:
TCS 1205; TCS1205; TCS-1205; 5-Nitro-α-oxo-N-(1R)-phenylethyl]-1H-indole-3-acetamide; 2-(5-nitro-1H-indol-3-yl)-2-oxo-N-[(1R)-1-phenylethyl]acetamide
MSDS:
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InChIKey:
VCKKJKQZHHPPDR-LLVKDONJSA-N
InChI:
InChI=1S/C18H15N3O4/c1-11(12-5-3-2-4-6-12)20-18(23)17(22)15-10-19-16-8-7-13(21(24)25)9-14(15)16/h2-11,19H,1H3,(H,20,23)/t11-/m1/s1
Canonical SMILES:
CC(C1=CC=CC=C1)NC(=O)C(=O)C2=CNC3=C2C=C(C=C3)[N+](=O)[O-]
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CAS 355022-97-8 TCS 1205

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