TC-E 5005 - CAS 959705-64-7
Category: Inhibitor
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Molecular Formula:
C15H18N4O
Molecular Weight:
270.33
COA:
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Targets:
Phosphodiesterase (PDE)
Description:
TC-E 5005 is a potent and selective PDE10A inhibitor (IC50 = 7.28, 239, 779, 919, 3100 and 3700 nM at PDE10A, 2A, 11A, 5A, 7B and 3A respectively, and >5000 nM at PDE1B, 4A, 6, 8A and 9A). TC-E 5005 reverses MK 801-induced hyperactivity and stereotypy in vivo. It also inhibits adrenergic and neurogenic smooth muscle contractions in the human prostate.
Brife Description:
PDE10A inhibitor
Purity:
≥99% by HPLC
Synonyms:
TC-E 5005; TC E-5005; TC E 5005; TC-E-5005; TCE5005; 2-Methoxy-6,7-dimethyl-9-propyl-imidazo[1,5-a]pyrido[3,2-e]pyrazine
MSDS:
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InChIKey:
YNADXFWEXJTQSZ-UHFFFAOYSA-N
InChI:
InChI=1S/C15H18N4O/c1-5-6-12-17-10(3)14-9(2)16-11-7-8-13(20-4)18-15(11)19(12)14/h7-8H,5-6H2,1-4H3
Canonical SMILES:
CCCC1=NC(=C2N1C3=C(C=CC(=N3)OC)N=C2C)C
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Chemical Structure

CAS 959705-64-7 TC-E 5005

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