TC-A 2317 hydrochloride - CAS 1245907-03-2
Category: Inhibitor
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Molecular Formula:
C19H28N6O.HCl
Molecular Weight:
392.93
COA:
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Targets:
Aurora Kinase
Description:
TC-A 2317 hydrochloride is a selective and potent Aurora kinase A (ARK-1) inhibitor (Ki = 1.2 nM and 101 nM for inhibition of Aurora kinase A and Aurora kinase B, respectively) with selectivity over 60 other kinases (IC50 > 1000 nM). TC-A 2317 exhibits great cell permeability and antitumor activity.
Brife Description:
Aurora kinase A (ARK-1) inhibitor
Purity:
≥98% by HPLC
Synonyms:
TC-A2317 HCl; TC-A2317 Hydrochloride; TCA2317 HCl; TC A2317 HCl; TC A2317 Hydrochloride; TCA2317 Hydrochloride; TC-A-2317 hydrochloride; 2-[(5-Hydroxy-1,5-dimethylhexyl)amino]-4-methyl-6-[(5-methyl-1H-pyrazol-3-yl)amino]-3-pyridinecarbonitrile hydrochloride
MSDS:
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InChIKey:
DXVATYHPJJPMIN-UHFFFAOYSA-N
InChI:
InChI=1S/C19H28N6O.ClH/c1-12-9-16(22-17-10-14(3)24-25-17)23-18(15(12)11-20)21-13(2)7-6-8-19(4,5)26;/h9-10,13,26H,6-8H2,1-5H3,(H3,21,22,23,24,25);1H
Canonical SMILES:
CC1=CC(=NC(=C1C#N)NC(C)CCCC(C)(C)O)NC2=NNC(=C2)C.Cl
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CAS 1245907-03-2 TC-A 2317 hydrochloride

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