|Description||Tazarotene could propel either early or late portions of the period leading to differentiation and G0 arrest and is interchangeable with an RARalpha-selective ligand.|
|B0084-055312||100 mg||$198||In stock|
|B0084-055312||250 mg||$398||In stock|
|Synonyms||AGN190168, AGN-190168; AGN 190168, Tazarotene, Fabior, Zorac|
RX-195183 is an RARα agonist (Kd=3 nM) with potential antineoplastic activity, modulating the transcription of genes responsible for cell differentiation and pr...
UVI 3003 is a selective and high affinity RXR antagonist. UVI 3003 does not affect the corepressor interaction capacity of the RARα subunit within the context o...
AC 261066 is a potent RARβ2 agonist (pEC50 = 8.1).
BMS 195614 is a neutral RAR α-selective antagonist (Ki = 2.5 nM) and exhibits no significant effect on nuclear receptor corepressor (NCoR) binding. BMS 195614 m...
Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma.
Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis ...
CD 2314 is a potent and selective RARβ receptor agonist (Kd = 145 and >3760 nM for RARβ and RARα receptors, respectively).
BMS 961 is a potent and selective RARγ agonist (EC50 = 30 and 1000 nM at RARγ and RARβ, respectively) displaying no activity at RARα receptors. It was found tha...