|Description||TASP 0433864 is a selective and positive allosteric modulator of mGlu2 receptor (EC50 = 199 and 206 nM for human and rat receptors, respectively) with no agonist activity at rat mGlu2 receptors. It displays weak activity against a range of neurotransmitter targets except 5-HT2B and MAO-B (72 and 92% inhibition at 10 μM, respectively).|
|Brife Description||positive allosteric modulator of mGlu2 receptor|
|Purity||≥98% by HPLC|
|Synonyms||TASP0433864, TASP0433864, TASP0433864; (2S)-2-[[4-(1,1-Dimethylethyl)phenoxy]methyl]-2,3-dihydro-5-methylimidazo[2,1-b]oxazole-6-carboxamide|
JNJ-42153605 is a selective positive allosteric modulator of the metabotropic glutamate 2 (mGlu2) receptor (EC50= 17 Nm) with an acceptable pharmacokinetic prof...
(±)-LY367385 is a selective mGlu1a antagonist.
(S)-4C3H-PG has been found to be a competitive GluR1 glutamate receptor antagonist as well as metabotropic GluR2/3 glutamate receptor agonist.
cis-ACPD has been found to be a potent NMDA receptor agonist as well as a mGluR agonist.
VU 0360172 hydrochloride
VU 0360172 hydrochloride is a positive allosteric modulator of mGlu5 receptors (EC50 = 16 nM; Ki = 195 nM) with potential antipsychotic-like activity. VU 036017...
FITM is a potent mGlu1 inhibitor (Ki = 2.5 nM) with great selectivity that does not disrupt mGlu5.
L-Glutamine is one of the 20 amino acids encoded by the standard genetic code.
VU 0361737 is a selective positive allosteric modulator (PAM) for mGlu4 receptor with EC50 of 240 nM and 110 nM at human and rat receptors, respectively, displa...