TASP 0433864 - CAS 1431980-60-7
Category: Inhibitor
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Molecular Formula:
C18H23N3O3
Molecular Weight:
329.39
COA:
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Targets:
mGluR
Description:
TASP 0433864 is a selective and positive allosteric modulator of mGlu2 receptor (EC50 = 199 and 206 nM for human and rat receptors, respectively) with no agonist activity at rat mGlu2 receptors. It displays weak activity against a range of neurotransmitter targets except 5-HT2B and MAO-B (72 and 92% inhibition at 10 μM, respectively).
Brife Description:
positive allosteric modulator of mGlu2 receptor
Purity:
≥98% by HPLC
Synonyms:
TASP0433864, TASP0433864, TASP0433864; (2S)-2-[[4-(1,1-Dimethylethyl)phenoxy]methyl]-2,3-dihydro-5-methylimidazo[2,1-b]oxazole-6-carboxamide
MSDS:
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InChIKey:
IZYYTLCSQBACIP-AWEZNQCLSA-N
InChI:
InChI=1S/C18H23N3O3/c1-11-15(16(19)22)20-17-21(11)9-14(24-17)10-23-13-7-5-12(6-8-13)18(2,3)4/h5-8,14H,9-10H2,1-4H3,(H2,19,22)/t14-/m0/s1
Canonical SMILES:
CC1=C(N=C2N1CC(O2)COC3=CC=C(C=C3)C(C)(C)C)C(=O)N
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Chemical Structure

CAS 1431980-60-7 TASP 0433864

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