Taltobulin - CAS 228266-40-8
Catalog number: 228266-40-8
Category: ADCs
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C27H43N3O4
Molecular Weight:
473.32
COA:
Inquire
Tag:
ADCs Cytotoxin
Description:
Taltobulin, also known as HTI-286 and SPA-110, is a fully synthetic analog of the natural tripeptide hemiasterlin, inhibits tubulin polymerization and circumvents transport-based resistance to taxanes. HTI-286 was a potent inhibitor of proliferation (mean IC50 = 2.5 ± 2.1 nm in 18 human tumor cell lines) and had substantially less interaction with multidrug resistance protein (P-glycoprotein) than currently used antimicrotubule agents, including paclitaxel, docetaxel, vinorelbine, or vinblastine.
Purity:
≥98.0% (HPLC)
Appearance:
White solid powder
Solubility:
Soluble in DMSO, not in water
Storage:
Dry, dark and at 0 - 4 °C for short term (days to weeks) or -20 °C for long term (months to years).
MSDS:
Inquire
Application:
ADCs Cytotoxin
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related ADCs Cytotoxin Products


CAS 58957-92-9 Idarubicin

Idarubicin
(CAS: 58957-92-9)

Idarubicin is an anthracycline antibiotic and a DNA topoisomerase II (topo II) inhibitor for MCF-7 cells with IC50 of 3.3 ng/mL.

CAS 61939-05-7 Desoxypeganine hydrochloride

Desoxypeganine hydrochloride
(CAS: 61939-05-7)

A substance which inhibits cholinesterases reversibly. Alkaloid , from plants of the Zygophyllaceae family

CAS 1449-89-4 Mebicyphat

Mebicyphat
(CAS: 1449-89-4)

Mebicyphat is shown to be a non-competitive GABA antagonist. Blocks GABA gated Cl- channels, and is shown to inhibit dihydropicrotoxin

CAS 526-06-7 Eudesmine

Eudesmine
(CAS: 526-06-7)

Lignan , from plants of the Rutaceae family, a substance presenting an estrogenic activity and sedative effects. .

CAS 480-39-7 Pinocembrin

Pinocembrin
(CAS: 480-39-7)

Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option i...

CAS 11103-72-3 Ruthenium Red

Ruthenium Red
(CAS: 11103-72-3)

Ruthenium red is a polycationic dye that inhibits sarcoplasmic reticulum Ca2+ release, blocks Ca2+ uptake and release from mitochondria, and prevents Ca2+ relea...

CAS 16408-77-8 Thalicminine

Thalicminine
(CAS: 16408-77-8)

Alkaloid, extracted from Thalictrum isopyroide.

M3-Nitrodienamine

Nitrodienamine, an inhibitor of Ca2+/Mg2+ ATPase.

Chemical Structure

CAS 228266-40-8 Taltobulin

Quick Inquiry

Verification code

Featured Items