|Description||Tadalafil binds to PDE5 with KD of 2.4 nM.|
|Synonyms||IC351, IC-351, IC 351, Tadalafil, Adcirca, Cialis|
K134 is a selective phosphodiesterase 3 (PDE3) inhibitor, and has been shown to exhibit more potent anti-platelet activity than cilostazol. In vivo studies have...
Aminophylline is a competitive nonselective phosphodiesterase inhibitor with an IC50 of 0.12 mM and also a nonselective adenosine receptor antagonist.
PDE10-IN-1 is a potent PDE10-IN-1 inhibi
PDE10-IN-1 is a potent PDE10-IN-1 inhibitor which can be used to treat CNS disorders and metabolic disorders.
A phosphodiesterase (PDE5) inhibitor, used to treat erectile dysfunction.
PDE1-IN-1 is a potent PDE1 inhibitor and neuroprotective agent.
PF-8380 blocks inflammation-induced LPA synthesis. PF-8380 works both in vitro and in vivo through direct inhibition of autotaxin. In human whole blood PF-8380 ...
Sildenafil, a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5), is a well-tolerated and highly effective tr...
The citrate salt form of Carbazeran, which has been found to be an aldehyde oxidase (AO) substrate as well as a non-specific PDE inhibitor.