|Description||T0070907 was identified as a potent and selective PPARgamma antagonist. T0070907 blocked PPARgamma function in both cell-based reporter gene and adipocyte differentiation assays. T0070907 is a novel tool for the study of PPARgamma/RXRalpha heterodimer function.|
|Synonyms||T-0070907; T 0070907.|
Seladelpar is a selective peroxisome proliferator-activated receptor -δ receptor agonist. Phase II clinical trials for the treatment of Hyperlipidaemia, Hyperli...
WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with EC50 of 1.5 μM.
SR 202 is a selective PPARγ antagonist used as an antidiabetic and antiobesity agent. SR 202 inhibits PPARγ-dependent adipocyte differentiation and growth in vi...
PPARγ is a ligand-activated nuclear receptor and was reported to plays a role in energy metabolism, glucose homeostasis and microglia-mediated neuroinflammation...
GW-9820 is a PPAR-gamma agonist with potential antidiabetic effect.
Protopanaxatriol is a dammarane-type tetracyclic triterpene sapogenins found in ginseng (Panax ginseng) and in notoginseng (Panax pseudoginseng). It may have a ...
Tesaglitazar is a dual-acting agonist of PPARα/γ (IC50 = 0.35 and 3.8 μM for PPARγ and PPARα, respectively). It reduces insulin resistance in obese Zucker rats ...
S26948 is a selective PPARγ agonist (EC50 = 8.83 nM). It promotes normal adipocyte differentiation and exhibits a lipid-lowering effect, decreasing the risk of ...