|Tag||ADCs Cytotoxin with Linkers|
|Description||DM4 with a reactive linker sulfo-SPDB, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site.|
|Synonyms||Maytansinoid DM4- succinimidyl 4-(N-maleimidomethyl)cyclohexane-3-sulfo-carboxylate|
Vc-MMAD consists the ADCs linker(Val-Cit) and potent tubulin inhibitor (MMAD), Vc-MMAD is an antibody drug conjugate.
BA-3011 is a novel conditionally active biologic AXL-targeted antibody-drug conjugate used to treat solid tumor. The CAB technology is aimed to improve the sele...
DM4 with a reactive linker SMCC, which can react with antibody to make antibody drug conjugate. DM4 can bind to tubulin at or near the vinblastine-binding site.
Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate; Mc-MMAD is a protective group (maleimidocaproyl) -con...
Mc-MMAF is a protective group-conjugated MMAF, MMAF is an antitubulin agent that inhibit cell division by blocking the polymerization of tubulin and it has lowe...
Mc-MMAE is a protective group conjugated MMAE, MMAE inhibits tubulin polymerization so that it inhibits cell division.
Vat-Cit-PAB-MMAD is a protective group conjugated MMAD, MMAD is a toxin payload in antibody drug conjugate.
INNO-206 (Aldoxorubicin) is the 6-maleimidocaproyl hydrazone derivative prodrug of the anthracycline antibiotic doxorubicin (DOXO-EMCH) with antineoplastic acti...