SU11652 - CAS 326914-10-7
Catalog number: B0084-313239
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C22H27ClN4O2
Molecular Weight:
414.93
COA:
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Targets:
c-Kit | FGFR | FLT3 | PDGFR | VEGFR
Description:
SU11652 is a cell-permeable and sunitinib-like inhibitor of tyrosine kinase receptor (RTK) and angiogenesis with antineoplastic property. It selectively inhibits PDGFR-β, VEGFR2, FGFR1, FLT3 (IC50 values of 3, 27, 170 and 1.5 nM, respectively) and Kit family members (IC50=~10-500 nM).
Brife Description:
RTK inhibitor
Purity:
99%
Appearance:
Orange Solid
Synonyms:
SU-11652; 5-[(Z)-(5-chloro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-N-[2-(diethylamino)ethyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
MSDS:
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Melting Point:
>210°C (dec.)
InChIKey:
XPLJEFSRINKZLC-ATVHPVEESA-N
InChI:
InChI=1S/C22H27ClN4O2/c1-5-27(6-2)10-9-24-22(29)20-13(3)19(25-14(20)4)12-17-16-11-15(23)7-8-18(16)26-21(17)28/h7-8,11-12,25H,5-6,9-10H2,1-4H3,(H,24,29)(H,26,28)/b17-12-
Canonical SMILES:
CCN(CC)CCNC(=O)C1=C(NC(=C1C)C=C2C3=C(C=CC(=C3)Cl)NC2=O)C
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Chemical Structure

CAS 326914-10-7 SU11652

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