SSR128129E free acid - CAS 848463-13-8
Catalog number: 848463-13-8
Category: Inhibitor
Please be kindly noted products are not for therapeutic use. We do not sell to patients.
Molecular Formula:
C18H16N2O4
Molecular Weight:
324.33
COA:
Inquire
Targets:
FGFR
Description:
SSR128129E free acid is a multi-FGFR blocker with allosteric properties. It inhibits FGFR signaling by binding to the extracellular FGFR domain without affecting orthosteric FGF binding.
Purity:
>98%
Synonyms:
SSR free acid
MSDS:
Inquire
InChIKey:
SNMCWIDCSPHZRD-UHFFFAOYSA-N
InChI:
InChI=1S/C18H16N2O4/c1-10-15(20-8-4-3-5-14(20)17(10)24-2)16(21)11-6-7-13(19)12(9-11)18(22)23/h3-9H,19H2,1-2H3,(H,22,23)
Canonical SMILES:
CC1=C(N2C=CC=CC2=C1OC)C(=O)C3=CC(=C(C=C3)N)C(=O)O
Molecular Weight Calculator Molarity Calculator Solution Dilution Calculator

Related FGFR Products


CAS 872511-34-7 BGJ-398

BGJ-398
(CAS: 872511-34-7)

BGJ398, also known as NVP-BGJ398, is a pan FGFR kinase inhibitor, and is an orally bioavailable pan inhibitor of human fibroblast growth factor receptors (FGFRs...

CAS 1254473-64-7 LY2874455

LY2874455
(CAS: 1254473-64-7)

LY2874455 exhibits a potent activity against FGF/FGFR-mediated signaling in several cancer cell lines and shows an excellent broad spectrum of antitumor activit...

CAS 1310746-10-1 NVP-BGJ398 phosphate

NVP-BGJ398 phosphate
(CAS: 1310746-10-1)

Potent and selective inhibitor of fibroblast growth factor receptor (FGFR) tyrosine kinases 1, 2, 3 and 4 (with IC50 values of 0.9, 1.4, 1.0 and 60 nM for FGFR1...

CAS 1125780-41-7 SKLB610

SKLB610
(CAS: 1125780-41-7)

SKLB610 is a VEGFR inhibitor that potently suppresses human tumor angiogenesis. SKLB610 inhibited angiogenesis-related tyrosine kinase VEGFR2, fibroblast growth...

CAS 848318-25-2 SSR128129E

SSR128129E
(CAS: 848318-25-2)

SSR128129E (SSR) is an potent FGFR inhibitor, which inhibits fibroblast growth factor receptor (FGFR) signaling by binding to the extracellular FGFR domain with...

CAS 1707289-21-1 BLU-554

BLU-554
(CAS: 1707289-21-1)

BLU-554 is a potent and selective inhibitor of fibroblast growth factor receptor 4 (FGFR4) (IC50 = 5 nM), which is promisingly to be used for the treatment of h...

CAS 1035270-39-3 AZD-4547

AZD-4547
(CAS: 1035270-39-3)

AZD4547 is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. AZD4547 binds to and inhibit...

CAS 1612888-66-0 Alofanib

Alofanib
(CAS: 1612888-66-0)

Alofanib, also known as RPT835, is a potent and selective allosteric inhibitor of FGFR2 with potential anticancer activity. Alofanib blocks the extracellular pa...

Chemical Structure

CAS 848463-13-8 SSR128129E free acid

Quick Inquiry

Verification code

Featured Items